Relation of ?-Amylase Activity with Glucose and Anti-Gliadin IgA and IgG in Sera of Patients with Celiac Disease
Celiac disease (CD) is an inflammatory small intestinal disorder that can lead to severe villous atrophy, and malabsorption . Since the measurement of α-amylase activity is the most widely used biochemical test for the diagnosis of pancreatic and non pancreatic disease , therefore serum α-amylase we...
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College of Pharmacy University of Baghdad
2017-03-01
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Series: | Iraqi Journal of Pharmaceutical Sciences |
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doaj-90eaed29bc044c34a6103788fc21f0602020-11-24T21:42:09ZengCollege of Pharmacy University of BaghdadIraqi Journal of Pharmaceutical Sciences2521-35121683-35972017-03-012018186497Relation of ?-Amylase Activity with Glucose and Anti-Gliadin IgA and IgG in Sera of Patients with Celiac DiseaseSura A. Al-EmamiAliaa H. FarajDahlia M.R. Al-AbadiCeliac disease (CD) is an inflammatory small intestinal disorder that can lead to severe villous atrophy, and malabsorption . Since the measurement of α-amylase activity is the most widely used biochemical test for the diagnosis of pancreatic and non pancreatic disease , therefore serum α-amylase were studied in the present study in an attempt to evaluate the usefulness of this enzyme in the diagnosis of celiac disease and its relationship with anti gliadin IgA and IgG and serum glucose . Thirty one patients with celiac disease were studied and compared with twenty four healthy individuals . Significant elevation of α-amylase activity , glucose and anti gliadin IgA and IgG were observed in the sera of patients with celiac disease compared with the control group . Also a significant positive correlation between α-amylase activity and anti gliadin IgG were found in the present study in the sera of patients with celiac disease while a non significant correlation were found between α-amylase activity and anti gliadin IgA and glucose in the sera of the same patients of celiac disease. Keywords:- α-amylase , anti – gliadin IgA , IgG , glucose , celiac disease .http://bijps.uobaghdad.edu.iq/index.php/bijps/article/view/497 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Sura A. Al-Emami Aliaa H. Faraj Dahlia M.R. Al-Abadi |
spellingShingle |
Sura A. Al-Emami Aliaa H. Faraj Dahlia M.R. Al-Abadi Relation of ?-Amylase Activity with Glucose and Anti-Gliadin IgA and IgG in Sera of Patients with Celiac Disease Iraqi Journal of Pharmaceutical Sciences |
author_facet |
Sura A. Al-Emami Aliaa H. Faraj Dahlia M.R. Al-Abadi |
author_sort |
Sura A. Al-Emami |
title |
Relation of ?-Amylase Activity with Glucose and Anti-Gliadin IgA and IgG in Sera of Patients with Celiac Disease |
title_short |
Relation of ?-Amylase Activity with Glucose and Anti-Gliadin IgA and IgG in Sera of Patients with Celiac Disease |
title_full |
Relation of ?-Amylase Activity with Glucose and Anti-Gliadin IgA and IgG in Sera of Patients with Celiac Disease |
title_fullStr |
Relation of ?-Amylase Activity with Glucose and Anti-Gliadin IgA and IgG in Sera of Patients with Celiac Disease |
title_full_unstemmed |
Relation of ?-Amylase Activity with Glucose and Anti-Gliadin IgA and IgG in Sera of Patients with Celiac Disease |
title_sort |
relation of ?-amylase activity with glucose and anti-gliadin iga and igg in sera of patients with celiac disease |
publisher |
College of Pharmacy University of Baghdad |
series |
Iraqi Journal of Pharmaceutical Sciences |
issn |
2521-3512 1683-3597 |
publishDate |
2017-03-01 |
description |
Celiac disease (CD) is an inflammatory small intestinal disorder that can lead to severe villous atrophy, and malabsorption . Since the measurement of α-amylase activity is the most widely used biochemical test for the diagnosis of pancreatic and non pancreatic disease , therefore serum α-amylase were studied in the present study in an attempt to evaluate the usefulness of this enzyme in the diagnosis of celiac disease and its relationship with anti gliadin IgA and IgG and serum glucose . Thirty one patients with celiac disease were studied and compared with twenty four healthy individuals . Significant elevation of α-amylase activity , glucose and anti gliadin IgA and IgG were observed in the sera of patients with celiac disease compared with the control group . Also a significant positive correlation between α-amylase activity and anti gliadin IgG were found in the present study in the sera of patients with celiac disease while a non significant correlation were found between α-amylase activity and anti gliadin IgA and glucose in the sera of the same patients of celiac disease.
Keywords:- α-amylase , anti – gliadin IgA , IgG , glucose , celiac disease . |
url |
http://bijps.uobaghdad.edu.iq/index.php/bijps/article/view/497 |
work_keys_str_mv |
AT suraaalemami relationofamylaseactivitywithglucoseandantigliadinigaandigginseraofpatientswithceliacdisease AT aliaahfaraj relationofamylaseactivitywithglucoseandantigliadinigaandigginseraofpatientswithceliacdisease AT dahliamralabadi relationofamylaseactivitywithglucoseandantigliadinigaandigginseraofpatientswithceliacdisease |
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