Adipose-derived mesenchymal stem cells attenuate dialysis-induced peritoneal fibrosis by modulating macrophage polarization via interleukin-6

Adipose-derived mesenchymal stem cells attenuate dialysis-induced peritoneal fibrosis by modulating macrophage polarization via interleukin-6

Abstract Background Life-long peritoneal dialysis (PD) as a renal replacement therapy is limited by peritoneal fibrosis. Previous studies showed immunomodulatory and antifibrotic effects of adipose-derived mesenchymal stem cells (ADSCs) on peritoneal fibrosis. However, the role of the peritoneal mac...

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Bibliographic Details
Main Authors: Chih-Yu Yang, Pu-Yuan Chang, Jun-Yi Chen, Bo-Sheng Wu, An-Hang Yang, Oscar Kuang-Sheng Lee
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Stem Cell Research & Therapy
Subjects:
Adipose-derived mesenchymal stem cell
Peritoneal dialysis
Peritoneal fibrosis
Macrophage
Interleukin-6
Online Access:https://doi.org/10.1186/s13287-021-02270-4

Internet

https://doi.org/10.1186/s13287-021-02270-4

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