Gender susceptibility to mycobacterial infections in patients with non-CF bronchiectasis
Non-tuberculous mycobacteria (NTM) are environmental microbes that cause a variety of diseases both in immunocompromised and immunocompetent patients. Epidemiologic data indicate that there has been a global rise in the incidence of NTM infections. It has also been noted that NTM infections have a p...
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Wolters Kluwer Medknow Publications
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doaj-9123de7f29b34839804b5b34fe36a1d62020-11-24T22:46:04ZengWolters Kluwer Medknow PublicationsInternational Journal of Mycobacteriology2212-55312212-554X2015-01-0142929610.1016/j.ijmyco.2015.05.002Gender susceptibility to mycobacterial infections in patients with non-CF bronchiectasisMehdi MirsaeidiRuxana T SadikotNon-tuberculous mycobacteria (NTM) are environmental microbes that cause a variety of diseases both in immunocompromised and immunocompetent patients. Epidemiologic data indicate that there has been a global rise in the incidence of NTM infections. It has also been noted that NTM infections have a predilection to occur in postmenopausal women. In a recent study, it was demonstrated that in patients with non-CF bronchiectasis the probability of NTM isolation was significantly higher in elderly female patients and in those with a low body mass index. However, the mechanisms of causality of these gender differences and morpho-phenotypes remain enigmatic. The present study reviews the data and plausible mechanisms which might provide clues to this gender susceptibility and morpho-phenotypes of patients with bronchiectasis and NTM.http://www.ijmyco.org/article.asp?issn=2212-5531;year=2015;volume=4;issue=2;spage=92;epage=96;aulast=MirsaeidiNontuberculous mycobacteriaBronchiectasisWomanGender |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Mehdi Mirsaeidi Ruxana T Sadikot |
spellingShingle |
Mehdi Mirsaeidi Ruxana T Sadikot Gender susceptibility to mycobacterial infections in patients with non-CF bronchiectasis International Journal of Mycobacteriology Nontuberculous mycobacteria Bronchiectasis Woman Gender |
author_facet |
Mehdi Mirsaeidi Ruxana T Sadikot |
author_sort |
Mehdi Mirsaeidi |
title |
Gender susceptibility to mycobacterial infections in patients with non-CF bronchiectasis |
title_short |
Gender susceptibility to mycobacterial infections in patients with non-CF bronchiectasis |
title_full |
Gender susceptibility to mycobacterial infections in patients with non-CF bronchiectasis |
title_fullStr |
Gender susceptibility to mycobacterial infections in patients with non-CF bronchiectasis |
title_full_unstemmed |
Gender susceptibility to mycobacterial infections in patients with non-CF bronchiectasis |
title_sort |
gender susceptibility to mycobacterial infections in patients with non-cf bronchiectasis |
publisher |
Wolters Kluwer Medknow Publications |
series |
International Journal of Mycobacteriology |
issn |
2212-5531 2212-554X |
publishDate |
2015-01-01 |
description |
Non-tuberculous mycobacteria (NTM) are environmental microbes that cause a variety of diseases both in immunocompromised and immunocompetent patients. Epidemiologic data indicate that there has been a global rise in the incidence of NTM infections. It has also been noted that NTM infections have a predilection to occur in postmenopausal women. In a recent study, it was demonstrated that in patients with non-CF bronchiectasis the probability of NTM isolation was significantly higher in elderly female patients and in those with a low body mass index. However, the mechanisms of causality of these gender differences and morpho-phenotypes remain enigmatic. The present study reviews the data and plausible mechanisms which might provide clues to this gender susceptibility and morpho-phenotypes of patients with bronchiectasis and NTM. |
topic |
Nontuberculous mycobacteria Bronchiectasis Woman Gender |
url |
http://www.ijmyco.org/article.asp?issn=2212-5531;year=2015;volume=4;issue=2;spage=92;epage=96;aulast=Mirsaeidi |
work_keys_str_mv |
AT mehdimirsaeidi gendersusceptibilitytomycobacterialinfectionsinpatientswithnoncfbronchiectasis AT ruxanatsadikot gendersusceptibilitytomycobacterialinfectionsinpatientswithnoncfbronchiectasis |
_version_ |
1725686297478037504 |