MUL1 acts in parallel to the PINK1/parkin pathway in regulating mitofusin and compensates for loss of PINK1/parkin
Parkinson's disease (PD) genes PINK1 and parkin act in a common pathway that regulates mitochondrial integrity and quality. Identifying new suppressors of the pathway is important for finding new therapeutic strategies. In this study, we show that MUL1 suppresses PINK1 or parkin mutant phenotyp...
Main Authors: | Jina Yun, Rajat Puri, Huan Yang, Michael A Lizzio, Chunlai Wu, Zu-Hang Sheng, Ming Guo |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2014-06-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/01958 |
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