Assessment of Ventilation and Perfusion in Patients with COVID-19 Discloses Unique Information of Pulmonary Function to a Clinician: Case Reports of V/P SPECT

Assessment of Ventilation and Perfusion in Patients with COVID-19 Discloses Unique Information of Pulmonary Function to a Clinician: Case Reports of V/P SPECT

V/P SPECT from 4 consecutive patients with COVID-19 suggests that ventilation and perfusion images may be applied to diagnose or exclude pulmonary embolism, verify nonsegmental diversion of perfusion from the ventilated areas (dead space ventilation) that may represent inflammation of the pulmonary...

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Main Authors: Marika Bajc, Fredrik Hedeer, Ari Lindqvist, Elin Trägårdh
Format: Article
Language:English
Published: SAGE Publishing 2021-07-01
Series:Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine
Online Access:https://doi.org/10.1177/11795484211030159
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spelling doaj-917b195d575c46b5a623b63c142da69f2021-07-20T21:33:23ZengSAGE PublishingClinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine1179-54842021-07-011510.1177/11795484211030159Assessment of Ventilation and Perfusion in Patients with COVID-19 Discloses Unique Information of Pulmonary Function to a Clinician: Case Reports of V/P SPECTMarika Bajc0Fredrik Hedeer1Ari Lindqvist2Elin Trägårdh3Department of Clinical Physiology and Nuclear Medicine, Skåne University Hospital Lund, 22185, Lund, SwedenDepartment of Clinical Physiology and Nuclear Medicine, Skåne University Hospital Lund, 22185, Lund, SwedenResearch Unit of Pulmonary Diseases, Clinical Research Institute HUCH Ltd., Helsinki University Hospital HUS and Helsinki University, Helsinki, FinlandDepartment of Clinical Physiology and Nuclear Medicine, Skåne University Hospital Malmö, Lund University, Lund, SwedenV/P SPECT from 4 consecutive patients with COVID-19 suggests that ventilation and perfusion images may be applied to diagnose or exclude pulmonary embolism, verify nonsegmental diversion of perfusion from the ventilated areas (dead space ventilation) that may represent inflammation of the pulmonary vasculature, detect the reversed mismatch of poor ventilation and better preserved perfusion (shunt perfusion) in bilateral pulmonary inflammation and indicate redistribution of lung perfusion (antigravitational hyperperfusion) due to cardiac congestion. V/P mismatch and reversed mismatch may be extensive enough to diminish dramatically preserved matching ventilation/perfusion and to induce severe hypoxemia in COVID-19.https://doi.org/10.1177/11795484211030159
collection DOAJ
language English
format Article
sources DOAJ
author Marika Bajc
Fredrik Hedeer
Ari Lindqvist
Elin Trägårdh
spellingShingle Marika Bajc
Fredrik Hedeer
Ari Lindqvist
Elin Trägårdh
Assessment of Ventilation and Perfusion in Patients with COVID-19 Discloses Unique Information of Pulmonary Function to a Clinician: Case Reports of V/P SPECT
Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine
author_facet Marika Bajc
Fredrik Hedeer
Ari Lindqvist
Elin Trägårdh
author_sort Marika Bajc
title Assessment of Ventilation and Perfusion in Patients with COVID-19 Discloses Unique Information of Pulmonary Function to a Clinician: Case Reports of V/P SPECT
title_short Assessment of Ventilation and Perfusion in Patients with COVID-19 Discloses Unique Information of Pulmonary Function to a Clinician: Case Reports of V/P SPECT
title_full Assessment of Ventilation and Perfusion in Patients with COVID-19 Discloses Unique Information of Pulmonary Function to a Clinician: Case Reports of V/P SPECT
title_fullStr Assessment of Ventilation and Perfusion in Patients with COVID-19 Discloses Unique Information of Pulmonary Function to a Clinician: Case Reports of V/P SPECT
title_full_unstemmed Assessment of Ventilation and Perfusion in Patients with COVID-19 Discloses Unique Information of Pulmonary Function to a Clinician: Case Reports of V/P SPECT
title_sort assessment of ventilation and perfusion in patients with covid-19 discloses unique information of pulmonary function to a clinician: case reports of v/p spect
publisher SAGE Publishing
series Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine
issn 1179-5484
publishDate 2021-07-01
description V/P SPECT from 4 consecutive patients with COVID-19 suggests that ventilation and perfusion images may be applied to diagnose or exclude pulmonary embolism, verify nonsegmental diversion of perfusion from the ventilated areas (dead space ventilation) that may represent inflammation of the pulmonary vasculature, detect the reversed mismatch of poor ventilation and better preserved perfusion (shunt perfusion) in bilateral pulmonary inflammation and indicate redistribution of lung perfusion (antigravitational hyperperfusion) due to cardiac congestion. V/P mismatch and reversed mismatch may be extensive enough to diminish dramatically preserved matching ventilation/perfusion and to induce severe hypoxemia in COVID-19.
url https://doi.org/10.1177/11795484211030159
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AT fredrikhedeer assessmentofventilationandperfusioninpatientswithcovid19disclosesuniqueinformationofpulmonaryfunctiontoacliniciancasereportsofvpspect
AT arilindqvist assessmentofventilationandperfusioninpatientswithcovid19disclosesuniqueinformationofpulmonaryfunctiontoacliniciancasereportsofvpspect
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