The impact of various seed, accessibility and interaction constraints on sRNA target prediction- a systematic assessment

The impact of various seed, accessibility and interaction constraints on sRNA target prediction- a systematic assessment

Abstract Background Seed and accessibility constraints are core features to enable highly accurate sRNA target screens based on RNA-RNA interaction prediction. Currently, available tools provide different (sets of) constraints and default parameter sets. Thus, it is hard to impossible for users to e...

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Bibliographic Details
Main Authors: Martin Raden, Teresa Müller, Stefan Mautner, Rick Gelhausen, Rolf Backofen
Format: Article
Language:English
Published: BMC 2020-01-01
Series:BMC Bioinformatics
Subjects:
RNA-RNA interaction
sRNA
Target prediction
Seed
Accessibility
Constraints
Online Access:https://doi.org/10.1186/s12859-019-3143-4

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