Reduction of autophagy and increase in apoptosis correlates with a favorable clinical outcome in patients with rheumatoid arthritis treated with anti-TNF drugs
Abstract Background Autophagy has emerged as a key mechanism in the survival and function of T and B lymphocytes, and its activation was involved in apoptosis resistance in rheumatoid arthritis (RA). To investigate whether the relationship between autophagy and apoptosis may impact the response to t...
Main Authors: | M. Vomero, V. Manganelli, C. Barbati, T. Colasanti, A. Capozzi, A. Finucci, F. R. Spinelli, F. Ceccarelli, C. Perricone, S. Truglia, S. Morrone, R. Maggio, R. Misasi, M. Bombardieri, M. Di Franco, F. Conti, M. Sorice, G. Valesini, C. Alessandri |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-01-01
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Series: | Arthritis Research & Therapy |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13075-019-1818-x |
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