Liraglutide Protects Against Brain Amyloid-β<sub>1–42</sub> Accumulation in Female Mice with Early Alzheimer’s Disease-Like Pathology by Partially Rescuing Oxidative/Nitrosative Stress and Inflammation

Liraglutide Protects Against Brain Amyloid-β<sub>1–42</sub> Accumulation in Female Mice with Early Alzheimer’s Disease-Like Pathology by Partially Rescuing Oxidative/Nitrosative Stress and Inflammation

Alzheimer&#8217;s disease (AD) is the most common form of dementia worldwide, being characterized by the deposition of senile plaques, neurofibrillary tangles (enriched in the amyloid beta (A&#946;) peptide and hyperphosphorylated tau (p-tau), respectively) and memory loss. Aging, type 2 dia...

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Bibliographic Details
Main Authors: Ana I. Duarte, Emanuel Candeias, Inês N. Alves, Débora Mena, Daniela F. Silva, Nuno J. Machado, Elisa J. Campos, Maria S. Santos, Catarina R. Oliveira, Paula I. Moreira
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:International Journal of Molecular Sciences
Subjects:
alzheimer’s disease
brain protection
female sex
glp-1 mimetics
liraglutide
Online Access:https://www.mdpi.com/1422-0067/21/5/1746

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