NRF2 function in osteocytes is required for bone homeostasis and drives osteocytic gene expression
Osteocytes, the most abundant bone cell type, are derived from osteoblasts through a process in which they are embedded in an osteoid. We previously showed that nutrient restriction promotes the osteocyte transcriptional program and is associated with increased mitochondrial biogenesis. Here, we sho...
Main Authors: | Cristina Sánchez-de-Diego, Leonardo Pedrazza, Carolina Pimenta-Lopes, Arturo Martinez-Martinez, Norma Dahdah, José Antonio Valer, Pablo Garcia-Roves, Jose Luis Rosa, Francesc Ventura |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-04-01
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Series: | Redox Biology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2213231720310508 |
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