Current research of microinflammation on retinal degenerative diseases
Retinal degenerative diseases are kinds of leading cause of blindness characterized by photoreceptor apoptosis and progressive neuronal degeneration. A large body of research has shown the evidence of inflammation reaction in such diseases. Retinal neuroinflammation may be a main factor resulting in...
Main Authors: | , |
---|---|
Format: | Article |
Language: | English |
Published: |
Press of International Journal of Ophthalmology (IJO PRESS)
2021-06-01
|
Series: | Guoji Yanke Zazhi |
Subjects: | |
Online Access: | http://ies.ijo.cn/cn_publish/2021/6/202106011.pdf |
id |
doaj-91d54b7e41984d62a295809f6618b109 |
---|---|
record_format |
Article |
spelling |
doaj-91d54b7e41984d62a295809f6618b1092021-05-25T01:26:27ZengPress of International Journal of Ophthalmology (IJO PRESS)Guoji Yanke Zazhi1672-51232021-06-0121699699910.3980/j.issn.1672-5123.2021.6.11202106011Current research of microinflammation on retinal degenerative diseasesMeng-Mei He0Jian Zhou1Department of Ophthalmology, Xijing Hospital, Air Force Medical University; Eye Institute of PLA, Xi'an 710032, Shaanxi Province, ChinaDepartment of Ophthalmology, Xijing Hospital, Air Force Medical University; Eye Institute of PLA, Xi'an 710032, Shaanxi Province, ChinaRetinal degenerative diseases are kinds of leading cause of blindness characterized by photoreceptor apoptosis and progressive neuronal degeneration. A large body of research has shown the evidence of inflammation reaction in such diseases. Retinal neuroinflammation may be a main factor resulting in apoptosis of photoreceptors and neurodegeneration of retina. In addition, the inflammatory response is not only detected in the retina, but also in aqueous humor, vitreous and even in blood, which forms a persistently very low degree, and chronic inflammatory environment. In this review, we focus on the development of microinflammatory response and its predictor for disease outcomes.http://ies.ijo.cn/cn_publish/2021/6/202106011.pdfretinal degenerative diseasesinflammationinflammatory cytokinesbiomarker |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Meng-Mei He Jian Zhou |
spellingShingle |
Meng-Mei He Jian Zhou Current research of microinflammation on retinal degenerative diseases Guoji Yanke Zazhi retinal degenerative diseases inflammation inflammatory cytokines biomarker |
author_facet |
Meng-Mei He Jian Zhou |
author_sort |
Meng-Mei He |
title |
Current research of microinflammation on retinal degenerative diseases |
title_short |
Current research of microinflammation on retinal degenerative diseases |
title_full |
Current research of microinflammation on retinal degenerative diseases |
title_fullStr |
Current research of microinflammation on retinal degenerative diseases |
title_full_unstemmed |
Current research of microinflammation on retinal degenerative diseases |
title_sort |
current research of microinflammation on retinal degenerative diseases |
publisher |
Press of International Journal of Ophthalmology (IJO PRESS) |
series |
Guoji Yanke Zazhi |
issn |
1672-5123 |
publishDate |
2021-06-01 |
description |
Retinal degenerative diseases are kinds of leading cause of blindness characterized by photoreceptor apoptosis and progressive neuronal degeneration. A large body of research has shown the evidence of inflammation reaction in such diseases. Retinal neuroinflammation may be a main factor resulting in apoptosis of photoreceptors and neurodegeneration of retina. In addition, the inflammatory response is not only detected in the retina, but also in aqueous humor, vitreous and even in blood, which forms a persistently very low degree, and chronic inflammatory environment. In this review, we focus on the development of microinflammatory response and its predictor for disease outcomes. |
topic |
retinal degenerative diseases inflammation inflammatory cytokines biomarker |
url |
http://ies.ijo.cn/cn_publish/2021/6/202106011.pdf |
work_keys_str_mv |
AT mengmeihe currentresearchofmicroinflammationonretinaldegenerativediseases AT jianzhou currentresearchofmicroinflammationonretinaldegenerativediseases |
_version_ |
1721428126123163648 |