Laboratory Diagnosis of Respiratory Tract Infections in Children – the State of the Art
In the pediatric population, respiratory infections are the most common cause of physician visits. Although many respiratory illnesses are self-limiting viral infections that resolve with time and supportive care, it can be critical to identify the causative pathogen at an early stage of the disease...
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doaj-920edbeb3db3497686e1c65f9dfe224a2020-11-24T22:19:36ZengFrontiers Media S.A.Frontiers in Microbiology1664-302X2018-10-01910.3389/fmicb.2018.02478414725Laboratory Diagnosis of Respiratory Tract Infections in Children – the State of the ArtShubhagata Das0Sherry Dunbar1Yi-Wei Tang2Yi-Wei Tang3Global Scientific Affairs, Luminex Corporation, Austin, TX, United StatesGlobal Scientific Affairs, Luminex Corporation, Austin, TX, United StatesDepartment of Laboratory Medicine, Memorial Sloan Kettering Cancer Center, Weill Medical College of Cornell University, New York, NY, United StatesDepartment of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, Weill Medical College of Cornell University, New York, NY, United StatesIn the pediatric population, respiratory infections are the most common cause of physician visits. Although many respiratory illnesses are self-limiting viral infections that resolve with time and supportive care, it can be critical to identify the causative pathogen at an early stage of the disease in order to implement effective antimicrobial therapy and infection control. Over the last few years, diagnostics for respiratory infections have evolved substantially, with the development of novel assays and the availability of updated tests for newer strains of pathogens. Newer laboratory methods are rapid, highly sensitive and specific, and are gradually replacing the conventional gold standards, although the clinical utility of these assays is still under evaluation. This article reviews the current laboratory methods available for testing for respiratory pathogens and discusses the advantages and disadvantages of each approach.https://www.frontiersin.org/article/10.3389/fmicb.2018.02478/fullrespiratory tract infectionrespiratory viruspediatric populationrespiratory infection diagnosismolecular diagnostics |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Shubhagata Das Sherry Dunbar Yi-Wei Tang Yi-Wei Tang |
spellingShingle |
Shubhagata Das Sherry Dunbar Yi-Wei Tang Yi-Wei Tang Laboratory Diagnosis of Respiratory Tract Infections in Children – the State of the Art Frontiers in Microbiology respiratory tract infection respiratory virus pediatric population respiratory infection diagnosis molecular diagnostics |
author_facet |
Shubhagata Das Sherry Dunbar Yi-Wei Tang Yi-Wei Tang |
author_sort |
Shubhagata Das |
title |
Laboratory Diagnosis of Respiratory Tract Infections in Children – the State of the Art |
title_short |
Laboratory Diagnosis of Respiratory Tract Infections in Children – the State of the Art |
title_full |
Laboratory Diagnosis of Respiratory Tract Infections in Children – the State of the Art |
title_fullStr |
Laboratory Diagnosis of Respiratory Tract Infections in Children – the State of the Art |
title_full_unstemmed |
Laboratory Diagnosis of Respiratory Tract Infections in Children – the State of the Art |
title_sort |
laboratory diagnosis of respiratory tract infections in children – the state of the art |
publisher |
Frontiers Media S.A. |
series |
Frontiers in Microbiology |
issn |
1664-302X |
publishDate |
2018-10-01 |
description |
In the pediatric population, respiratory infections are the most common cause of physician visits. Although many respiratory illnesses are self-limiting viral infections that resolve with time and supportive care, it can be critical to identify the causative pathogen at an early stage of the disease in order to implement effective antimicrobial therapy and infection control. Over the last few years, diagnostics for respiratory infections have evolved substantially, with the development of novel assays and the availability of updated tests for newer strains of pathogens. Newer laboratory methods are rapid, highly sensitive and specific, and are gradually replacing the conventional gold standards, although the clinical utility of these assays is still under evaluation. This article reviews the current laboratory methods available for testing for respiratory pathogens and discusses the advantages and disadvantages of each approach. |
topic |
respiratory tract infection respiratory virus pediatric population respiratory infection diagnosis molecular diagnostics |
url |
https://www.frontiersin.org/article/10.3389/fmicb.2018.02478/full |
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