A novel immune subtype classification of ER-positive, PR-negative and HER2-negative breast cancer based on the genomic and transcriptomic landscape

A novel immune subtype classification of ER-positive, PR-negative and HER2-negative breast cancer based on the genomic and transcriptomic landscape

Abstract Background The diversity and plasticity behind ER+/PR−/HER2− breast cancer have not been widely explored. It is essential to identify heterogeneous microenvironment phenotypes and investigate specific genomic events driving the formation of these phenotypes. Methods Based on the immune-rela...

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Bibliographic Details
Main Authors: Peiling Xie, Rui An, Shibo Yu, Jianjun He, Huimin Zhang
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Journal of Translational Medicine
Subjects:
Breast cancer
ER+/PR−/HER2−
Immune classification
Multi-omics
Online Access:https://doi.org/10.1186/s12967-021-03076-x

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