Antiretroviral therapy for adults infected with HIV: Guidelines for health care professionals from the Quebec HIV care committee
The appropriate use of antiretrovirals reduces morbidity and mortality caused by HIV infection. The present article provides health care professionals with a practical guide for the use of antiretrovirals. Therapy should be initiated based predominantly on clinical presentation and CD4 count, and sh...
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Series: | Canadian Journal of Infectious Diseases and Medical Microbiology |
Online Access: | http://dx.doi.org/10.1155/2011/169045 |
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doaj-921429ef16984e138725b252f02cb83b2021-07-02T06:50:35ZengHindawi LimitedCanadian Journal of Infectious Diseases and Medical Microbiology1712-95322011-01-01222526010.1155/2011/169045Antiretroviral therapy for adults infected with HIV: Guidelines for health care professionals from the Quebec HIV care committeeDanielle Rouleau0Claude Fortin1Benoît Trottier2Richard Lalonde3Normand Lapointe4Pierre Côté5Jean-Pierre Routy6Marie-France Matte7Irina Tsarevsky8Jean-Guy Baril9for the Comité consultatif sur la prise en charge clinique des personnes vivant avec le VIH10Unité hospitalière de recherche, d’enseignement et de soins sur le sida (UHRESS), Centre hospitalier de l’Université de Montréal, CanadaUnité hospitalière de recherche, d’enseignement et de soins sur le sida (UHRESS), Centre hospitalier de l’Université de Montréal, CanadaUnité hospitalière de recherche, d’enseignement et de soins sur le sida (UHRESS), Centre hospitalier de l’Université de Montréal, CanadaUHRESS, McGill University Health Centre, CanadaUHRESS, Centre hospitalier universitaire Sainte-Justine, Université de Montréal, CanadaUnité hospitalière de recherche, d’enseignement et de soins sur le sida (UHRESS), Centre hospitalier de l’Université de Montréal, CanadaUHRESS, McGill University Health Centre, CanadaService de lutte contre les infections transmissibles sexuellement par le sang, Ministère de la Santé et des Services sociaux, Montréal, Québec, CanadaService de lutte contre les infections transmissibles sexuellement par le sang, Ministère de la Santé et des Services sociaux, Montréal, Québec, CanadaUnité hospitalière de recherche, d’enseignement et de soins sur le sida (UHRESS), Centre hospitalier de l’Université de Montréal, CanadaUnité hospitalière de recherche, d’enseignement et de soins sur le sida (UHRESS), Centre hospitalier de l’Université de Montréal, CanadaThe appropriate use of antiretrovirals reduces morbidity and mortality caused by HIV infection. The present article provides health care professionals with a practical guide for the use of antiretrovirals. Therapy should be initiated based predominantly on clinical presentation and CD4 count, and should consist of three active drugs or at least two active drugs when this is not possible, as in cases of some treatment-experienced patients. This is the most effective way to achieve long-term suppression of viral replication. Selection of individual drugs in the regimen should consider the weight of the evidence supporting these choices, as well as their tolerability profiles and ease of use, the patients’ comorbidities and treatment history. Treatment interruption is not recommended, either in aviremic patients or in those who have experienced virological failure. Instead, the therapeutic regimen should be adjusted to minimize side effects, promote adherence and suppress viral replication.http://dx.doi.org/10.1155/2011/169045 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Danielle Rouleau Claude Fortin Benoît Trottier Richard Lalonde Normand Lapointe Pierre Côté Jean-Pierre Routy Marie-France Matte Irina Tsarevsky Jean-Guy Baril for the Comité consultatif sur la prise en charge clinique des personnes vivant avec le VIH |
spellingShingle |
Danielle Rouleau Claude Fortin Benoît Trottier Richard Lalonde Normand Lapointe Pierre Côté Jean-Pierre Routy Marie-France Matte Irina Tsarevsky Jean-Guy Baril for the Comité consultatif sur la prise en charge clinique des personnes vivant avec le VIH Antiretroviral therapy for adults infected with HIV: Guidelines for health care professionals from the Quebec HIV care committee Canadian Journal of Infectious Diseases and Medical Microbiology |
author_facet |
Danielle Rouleau Claude Fortin Benoît Trottier Richard Lalonde Normand Lapointe Pierre Côté Jean-Pierre Routy Marie-France Matte Irina Tsarevsky Jean-Guy Baril for the Comité consultatif sur la prise en charge clinique des personnes vivant avec le VIH |
author_sort |
Danielle Rouleau |
title |
Antiretroviral therapy for adults infected with HIV: Guidelines for health care professionals from the Quebec HIV care committee |
title_short |
Antiretroviral therapy for adults infected with HIV: Guidelines for health care professionals from the Quebec HIV care committee |
title_full |
Antiretroviral therapy for adults infected with HIV: Guidelines for health care professionals from the Quebec HIV care committee |
title_fullStr |
Antiretroviral therapy for adults infected with HIV: Guidelines for health care professionals from the Quebec HIV care committee |
title_full_unstemmed |
Antiretroviral therapy for adults infected with HIV: Guidelines for health care professionals from the Quebec HIV care committee |
title_sort |
antiretroviral therapy for adults infected with hiv: guidelines for health care professionals from the quebec hiv care committee |
publisher |
Hindawi Limited |
series |
Canadian Journal of Infectious Diseases and Medical Microbiology |
issn |
1712-9532 |
publishDate |
2011-01-01 |
description |
The appropriate use of antiretrovirals reduces morbidity and mortality caused by HIV infection. The present article provides health care professionals with a practical guide for the use of antiretrovirals. Therapy should be initiated based predominantly on clinical presentation and CD4 count, and should consist of three active drugs or at least two active drugs when this is not possible, as in cases of some treatment-experienced patients. This is the most effective way to achieve long-term suppression of viral replication. Selection of individual drugs in the regimen should consider the weight of the evidence supporting these choices, as well as their tolerability profiles and ease of use, the patients’ comorbidities and treatment history. Treatment interruption is not recommended, either in aviremic patients or in those who have experienced virological failure. Instead, the therapeutic regimen should be adjusted to minimize side effects, promote adherence and suppress viral replication. |
url |
http://dx.doi.org/10.1155/2011/169045 |
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