Does Low-Magnitude High-Frequency Vibration (LMHFV) Worth for Clinical Trial on Dental Implant? A Systematic Review and Meta-Analysis on Animal Studies
Being as a non-pharmacological medical intervention, low-magnitude high-frequency vibration (LMHFV) has shown a positive effect on bone induction and remodeling for various muscle diseases in animal studies, among which dental implants osteointegration were reported to be improved as well. However,...
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doaj-921df3ea8c6345bfacfad114f2e5b4972021-04-27T07:09:08ZengFrontiers Media S.A.Frontiers in Bioengineering and Biotechnology2296-41852021-04-01910.3389/fbioe.2021.626892626892Does Low-Magnitude High-Frequency Vibration (LMHFV) Worth for Clinical Trial on Dental Implant? A Systematic Review and Meta-Analysis on Animal StudiesXinjian Ye0Ying Gu1Yijing Bai2Siqi Xia3Yujia Zhang4Yuwei Lou5Yuchi Zhu6Yuwei Dai7James Kit-Hon Tsoi8Shuhua Wang9Shuhua Wang10School of Stomatology, Zhejiang Chinese Medical University, Hangzhou, ChinaApplied Oral Sciences and Community Dental Care, Faculty of Dentistry, The University of Hong Kong, Pokfulam, Hong KongThe First Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, ChinaSchool of Stomatology, Zhejiang Chinese Medical University, Hangzhou, ChinaSchool of Stomatology, Zhejiang Chinese Medical University, Hangzhou, ChinaSchool of Stomatology, Zhejiang Chinese Medical University, Hangzhou, ChinaSchool of Stomatology, Zhejiang Chinese Medical University, Hangzhou, ChinaSchool of Stomatology, Zhejiang Chinese Medical University, Hangzhou, ChinaApplied Oral Sciences and Community Dental Care, Faculty of Dentistry, The University of Hong Kong, Pokfulam, Hong KongSchool of Stomatology, Zhejiang Chinese Medical University, Hangzhou, ChinaHospital of Stomatology, Zhejiang Chinese Medical University, Hangzhou, ChinaBeing as a non-pharmacological medical intervention, low-magnitude high-frequency vibration (LMHFV) has shown a positive effect on bone induction and remodeling for various muscle diseases in animal studies, among which dental implants osteointegration were reported to be improved as well. However, whether LMHFV can be clinically used in dental implant is still unknown. In this study, efficacy, parameters and side effects of LMHFV were analyzed via data before 15th July 2020, collecting from MEDLINE/PubMed, Embase, Ovid and Cochrane Library databases. In the screened 1,742 abstracts and 45 articles, 15 animal studies involving 972 implants were included. SYRCLE's tool was performed to assess the possible risk of bias for each study. The GRADE approach was applied to evaluate the quality of evidence. Random effects meta-analysis detected statistically significant in total BIC (P < 0.0001) and BV/TV (P = 0.001) upon loading LMHFV on implants. To conclude, LMHFV played an active role on BIC and BV/TV data according to the GRADE analysis results (medium and low quality of evidence). This might illustrate LMHFV to be a worthy way in improving osseointegration clinically, especially for osteoporosis.Systematic Review Registration:https://www.crd.york.ac.uk/PROSPERO, identifier: NCT02612389https://www.frontiersin.org/articles/10.3389/fbioe.2021.626892/fulllow-magnitude high-frequency vibrationosseointegrationosteoporosissystematic review and meta-analysisdental implant |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Xinjian Ye Ying Gu Yijing Bai Siqi Xia Yujia Zhang Yuwei Lou Yuchi Zhu Yuwei Dai James Kit-Hon Tsoi Shuhua Wang Shuhua Wang |
spellingShingle |
Xinjian Ye Ying Gu Yijing Bai Siqi Xia Yujia Zhang Yuwei Lou Yuchi Zhu Yuwei Dai James Kit-Hon Tsoi Shuhua Wang Shuhua Wang Does Low-Magnitude High-Frequency Vibration (LMHFV) Worth for Clinical Trial on Dental Implant? A Systematic Review and Meta-Analysis on Animal Studies Frontiers in Bioengineering and Biotechnology low-magnitude high-frequency vibration osseointegration osteoporosis systematic review and meta-analysis dental implant |
author_facet |
Xinjian Ye Ying Gu Yijing Bai Siqi Xia Yujia Zhang Yuwei Lou Yuchi Zhu Yuwei Dai James Kit-Hon Tsoi Shuhua Wang Shuhua Wang |
author_sort |
Xinjian Ye |
title |
Does Low-Magnitude High-Frequency Vibration (LMHFV) Worth for Clinical Trial on Dental Implant? A Systematic Review and Meta-Analysis on Animal Studies |
title_short |
Does Low-Magnitude High-Frequency Vibration (LMHFV) Worth for Clinical Trial on Dental Implant? A Systematic Review and Meta-Analysis on Animal Studies |
title_full |
Does Low-Magnitude High-Frequency Vibration (LMHFV) Worth for Clinical Trial on Dental Implant? A Systematic Review and Meta-Analysis on Animal Studies |
title_fullStr |
Does Low-Magnitude High-Frequency Vibration (LMHFV) Worth for Clinical Trial on Dental Implant? A Systematic Review and Meta-Analysis on Animal Studies |
title_full_unstemmed |
Does Low-Magnitude High-Frequency Vibration (LMHFV) Worth for Clinical Trial on Dental Implant? A Systematic Review and Meta-Analysis on Animal Studies |
title_sort |
does low-magnitude high-frequency vibration (lmhfv) worth for clinical trial on dental implant? a systematic review and meta-analysis on animal studies |
publisher |
Frontiers Media S.A. |
series |
Frontiers in Bioengineering and Biotechnology |
issn |
2296-4185 |
publishDate |
2021-04-01 |
description |
Being as a non-pharmacological medical intervention, low-magnitude high-frequency vibration (LMHFV) has shown a positive effect on bone induction and remodeling for various muscle diseases in animal studies, among which dental implants osteointegration were reported to be improved as well. However, whether LMHFV can be clinically used in dental implant is still unknown. In this study, efficacy, parameters and side effects of LMHFV were analyzed via data before 15th July 2020, collecting from MEDLINE/PubMed, Embase, Ovid and Cochrane Library databases. In the screened 1,742 abstracts and 45 articles, 15 animal studies involving 972 implants were included. SYRCLE's tool was performed to assess the possible risk of bias for each study. The GRADE approach was applied to evaluate the quality of evidence. Random effects meta-analysis detected statistically significant in total BIC (P < 0.0001) and BV/TV (P = 0.001) upon loading LMHFV on implants. To conclude, LMHFV played an active role on BIC and BV/TV data according to the GRADE analysis results (medium and low quality of evidence). This might illustrate LMHFV to be a worthy way in improving osseointegration clinically, especially for osteoporosis.Systematic Review Registration:https://www.crd.york.ac.uk/PROSPERO, identifier: NCT02612389 |
topic |
low-magnitude high-frequency vibration osseointegration osteoporosis systematic review and meta-analysis dental implant |
url |
https://www.frontiersin.org/articles/10.3389/fbioe.2021.626892/full |
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