The findings of optical coherence tomography of retinal degeneration in relation to the morphological and electroretinographic features in RPE65-/- mice.

PURPOSE:Mutations of the gene encoding RPE65 cause Leber congenital amaurosis (LCA) retinitis pigmentosa (RP). The optical coherence tomography (OCT) is increasingly utilized to noninvasively evaluate various types of retinal diseases, including RP. The present study was conducted to characterize th...

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Bibliographic Details
Main Authors: Reiko Tanabu, Kota Sato, Natsuki Monai, Kodai Yamauchi, Takayuki Gonome, Yuting Xie, Shizuka Takahashi, Sei-Ichi Ishiguro, Mitsuru Nakazawa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0210439