Diverse regulatory manners of human telomerase reverse transcriptase

Diverse regulatory manners of human telomerase reverse transcriptase

Abstract Human telomerase reverse transcriptase (hTERT) is the core subunit of human telomerase and plays important roles in human cancers. Aberrant expression of hTERT is closely associated with tumorigenesis, cancer cell stemness maintaining, cell proliferation, apoptosis inhibition, senescence ev...

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Bibliographic Details
Main Authors: Meng-Meng Jie, Xing Chang, Shuo Zeng, Cheng Liu, Guo-Bin Liao, Ya-Ran Wu, Chun-Hua Liu, Chang-Jiang Hu, Shi-Ming Yang, Xin-Zhe Li
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Cell Communication and Signaling
Subjects:
hTERT
Regulation
Transcription
Post-transcription
Post-translational modification
Online Access:http://link.springer.com/article/10.1186/s12964-019-0372-0

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