Personalized B cell response to the Lactobacillus rhamnosus GG probiotic in healthy human subjects: a randomized trial

Personalized B cell response to the Lactobacillus rhamnosus GG probiotic in healthy human subjects: a randomized trial

The specific effects of administering live probiotics in the human gut are not well characterized. To this end, we investigated the immediate effect of Lactobacillus rhamnosus GG (LGG) in the jejunum of 27 healthy volunteers 2 h after ingestion using a combination of global RNA sequencing of human b...

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Bibliographic Details
Main Authors: Jette Bornholdt, Christa Broholm, Yun Chen, Alfredo Rago, Stine Sloth, Jakob Hendel, Cathrine Melsæther, Christina V. Müller, Maria Juul Nielsen, Jesper Strickertsson, Lars Engelholm, Kristoffer Vitting-Seerup, Kim B. Jensen, Adam Baker, Albin Sandelin
Format: Article
Language:English
Published: Taylor & Francis Group 2020-11-01
Series:Gut Microbes
Subjects:
lactobacillus rhamnosus gg
immediate in vivo effect
probiotics
human transcriptomics
b cell activation
Online Access:http://dx.doi.org/10.1080/19490976.2020.1854639

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