The Sensitivity and Specificity of High Sensitive CRP, D-Dimer and IL-6 in Acute Coronary Syndrome
Objective: ACS is the life threatening causes of chest pain. The aim of this study is to detect the sensitivity and specificity of CRP, IL-6 and D-dimer and identify their role in predicting adverse cardiac events. Material and Methods: All patients describing typical chest pain were enrolled in the...
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2011-11-01
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doaj-92470c2698174e8c9fe287d22cb2ec772020-11-25T00:02:44ZengGalenos Publishing HouseBalkan Medical Journal2146-31232146-31312011-11-012804429434The Sensitivity and Specificity of High Sensitive CRP, D-Dimer and IL-6 in Acute Coronary SyndromeÖzlem YiğitYıldıray CeteCenker EkenErkan GöksuObjective: ACS is the life threatening causes of chest pain. The aim of this study is to detect the sensitivity and specificity of CRP, IL-6 and D-dimer and identify their role in predicting adverse cardiac events. Material and Methods: All patients describing typical chest pain were enrolled in the study. Demographic features and final diagnosis were written and serum specimens were collected. All patients were telephoned after one month to determine if there were any adverse cardiac events. Results: There were 132 patients, (94 male, 38 female). The mean age was 60.92±10.78. 55 patients were diagnosed as AMI (37 STEMI and 18 NSTEMI) 60 patients as unstable angina pectoris, 15 patients as stable angina pectoris and 2 patients as non cardiac chest pain. 6 patients died in the hospital. 15 patients had adverse cardiac events (12 recurrent AMI, 2 sudden cardiac death, 1 stroke). The levels of D-dimer, CRP and IL-6 at the presentation were not predictive for adverse events. Conclusion: D-dimer, CRP and IL-6 levels were high both in ACS and stable angina. Detecting the predictive value for adverse cardiac events requires larger patient numbers and longer follow up times. http://balkanmedicaljournal.org/text.php3?id=807Acute coronary syndromeCRPD-dimerIL-6 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Özlem Yiğit Yıldıray Cete Cenker Eken Erkan Göksu |
spellingShingle |
Özlem Yiğit Yıldıray Cete Cenker Eken Erkan Göksu The Sensitivity and Specificity of High Sensitive CRP, D-Dimer and IL-6 in Acute Coronary Syndrome Balkan Medical Journal Acute coronary syndrome CRP D-dimer IL-6 |
author_facet |
Özlem Yiğit Yıldıray Cete Cenker Eken Erkan Göksu |
author_sort |
Özlem Yiğit |
title |
The Sensitivity and Specificity of High Sensitive CRP, D-Dimer and IL-6 in Acute Coronary Syndrome |
title_short |
The Sensitivity and Specificity of High Sensitive CRP, D-Dimer and IL-6 in Acute Coronary Syndrome |
title_full |
The Sensitivity and Specificity of High Sensitive CRP, D-Dimer and IL-6 in Acute Coronary Syndrome |
title_fullStr |
The Sensitivity and Specificity of High Sensitive CRP, D-Dimer and IL-6 in Acute Coronary Syndrome |
title_full_unstemmed |
The Sensitivity and Specificity of High Sensitive CRP, D-Dimer and IL-6 in Acute Coronary Syndrome |
title_sort |
sensitivity and specificity of high sensitive crp, d-dimer and il-6 in acute coronary syndrome |
publisher |
Galenos Publishing House |
series |
Balkan Medical Journal |
issn |
2146-3123 2146-3131 |
publishDate |
2011-11-01 |
description |
Objective: ACS is the life threatening causes of chest pain. The aim of this study is to detect the sensitivity and specificity of CRP, IL-6 and D-dimer and identify their role in predicting adverse cardiac events. Material and Methods: All patients describing typical chest pain were enrolled in the study. Demographic features and final diagnosis were written and serum specimens were collected. All patients were telephoned after one month to determine if there were any adverse cardiac events. Results: There were 132 patients, (94 male, 38 female). The mean age was 60.92±10.78. 55 patients were diagnosed as AMI (37 STEMI and 18 NSTEMI) 60 patients as unstable angina pectoris, 15 patients as stable angina pectoris and 2 patients as non cardiac chest pain. 6 patients died in the hospital. 15 patients had adverse cardiac events (12 recurrent AMI, 2 sudden cardiac death, 1 stroke). The levels of D-dimer, CRP and IL-6 at the presentation were not predictive for adverse events. Conclusion: D-dimer, CRP and IL-6 levels were high both in ACS and stable angina. Detecting the predictive value for adverse cardiac events requires larger patient numbers and longer follow up times. |
topic |
Acute coronary syndrome CRP D-dimer IL-6 |
url |
http://balkanmedicaljournal.org/text.php3?id=807 |
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