Assessing Candidate Gene nsSNPs for Phenotypic Differences in Double-Strand Break Repair Using Radiation-Induced γH2A.X Foci

Assessing Candidate Gene nsSNPs for Phenotypic Differences in Double-Strand Break Repair Using Radiation-Induced γH2A.X Foci

Nonsynonymous SNPs (nsSNPs) in DNA repair genes may be important determinants of DNA damage and cancer risk. We applied a set of screening criteria to a large number of nsSNPs and selected a subset of SNPs that were likely candidates for phenotypic effects on DNA double-strand break repair (DSBR). I...

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Bibliographic Details
Main Authors:	Christina A. Markunas, David M. Umbach, Zongli Xu, Jack A. Taylor
Format:	Article
Language:	English
Published:	Hindawi Limited 2008-01-01
Series:	Journal of Cancer Epidemiology
Online Access:	http://dx.doi.org/10.1155/2008/387423

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