Epigenome-wide DNA methylation in hearing ability: new mechanisms for an old problem.
Epigenetic regulation of gene expression has been shown to change over time and may be associated with environmental exposures in common complex traits. Age-related hearing impairment is a complex disorder, known to be heritable, with heritability estimates of 57-70%. Epigenetic regulation might exp...
Main Authors: | Lisa E Wolber, Claire J Steves, Pei-Chien Tsai, Panos Deloukas, Tim D Spector, Jordana T Bell, Frances M K Williams |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4153547?pdf=render |
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