Staphylococcus aureus alpha-hemolysin activates the NLRP3-inflammasome in human and mouse monocytic cells.
Community Acquired Methicillin Resistant Staphylococcus aureus (CA-MRSA) causes severe necrotizing infections of the skin, soft tissues, and lungs. Staphylococcal alpha-hemolysin is an essential virulence factor in mouse models of CA-MRSA necrotizing pneumonia. S. aureus alpha-hemolysin has long bee...
Main Authors: | Robin R Craven, Xi Gao, Irving C Allen, Denis Gris, Juliane Bubeck Wardenburg, Erin McElvania-Tekippe, Jenny P Ting, Joseph A Duncan |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-10-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2758589?pdf=render |
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