A randomized trial of amphotericin B alone or in combination with itraconazole in the treatment of mucocutaneous leishmaniasis

A randomized trial of amphotericin B alone or in combination with itraconazole in the treatment of mucocutaneous leishmaniasis

A randomized trial of amphotericin B (AB) alone and in combination with oral itraconazole (IZ) is carried out in two groups of 10 mucocutaneous leishmaniasis patients from Bolivia and Peru. AB+IZ combination is no better than AB monotherapy, as far as efficacy and tolerability are concerned. No anta...

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Main Authors: Luis Valda Rodriguez, Jean-Pierre Dedet, Virginia Paredtes, Carmelo Mendoza, Fernando Cardenas
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 1995-08-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
mucocutaneous leishmaniasis
treatmetn
amphotericin B
itraconazole
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761995000400020
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spelling doaj-9266081bbc894e9bae28167f406e18942020-11-25T00:19:13ZengInstituto Oswaldo Cruz, Ministério da SaúdeMemórias do Instituto Oswaldo Cruz.0074-02761678-80601995-08-0190452552810.1590/S0074-02761995000400020A randomized trial of amphotericin B alone or in combination with itraconazole in the treatment of mucocutaneous leishmaniasisLuis Valda RodriguezJean-Pierre DedetVirginia ParedtesCarmelo MendozaFernando CardenasA randomized trial of amphotericin B (AB) alone and in combination with oral itraconazole (IZ) is carried out in two groups of 10 mucocutaneous leishmaniasis patients from Bolivia and Peru. AB+IZ combination is no better than AB monotherapy, as far as efficacy and tolerability are concerned. No antagonism was detected.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761995000400020mucocutaneous leishmaniasistreatmetnamphotericin Bitraconazole
collection DOAJ
language English
format Article
sources DOAJ
author Luis Valda Rodriguez
Jean-Pierre Dedet
Virginia Paredtes
Carmelo Mendoza
Fernando Cardenas
spellingShingle Luis Valda Rodriguez
Jean-Pierre Dedet
Virginia Paredtes
Carmelo Mendoza
Fernando Cardenas
A randomized trial of amphotericin B alone or in combination with itraconazole in the treatment of mucocutaneous leishmaniasis
Memórias do Instituto Oswaldo Cruz.
mucocutaneous leishmaniasis
treatmetn
amphotericin B
itraconazole
author_facet Luis Valda Rodriguez
Jean-Pierre Dedet
Virginia Paredtes
Carmelo Mendoza
Fernando Cardenas
author_sort Luis Valda Rodriguez
title A randomized trial of amphotericin B alone or in combination with itraconazole in the treatment of mucocutaneous leishmaniasis
title_short A randomized trial of amphotericin B alone or in combination with itraconazole in the treatment of mucocutaneous leishmaniasis
title_full A randomized trial of amphotericin B alone or in combination with itraconazole in the treatment of mucocutaneous leishmaniasis
title_fullStr A randomized trial of amphotericin B alone or in combination with itraconazole in the treatment of mucocutaneous leishmaniasis
title_full_unstemmed A randomized trial of amphotericin B alone or in combination with itraconazole in the treatment of mucocutaneous leishmaniasis
title_sort randomized trial of amphotericin b alone or in combination with itraconazole in the treatment of mucocutaneous leishmaniasis
publisher Instituto Oswaldo Cruz, Ministério da Saúde
series Memórias do Instituto Oswaldo Cruz.
issn 0074-0276
1678-8060
publishDate 1995-08-01
description A randomized trial of amphotericin B (AB) alone and in combination with oral itraconazole (IZ) is carried out in two groups of 10 mucocutaneous leishmaniasis patients from Bolivia and Peru. AB+IZ combination is no better than AB monotherapy, as far as efficacy and tolerability are concerned. No antagonism was detected.
topic mucocutaneous leishmaniasis
treatmetn
amphotericin B
itraconazole
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761995000400020
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