A time-released osmotic pump fabricated by compression-coated method: Formulation screen, mechanism research and pharmacokinetic study

A time-released osmotic pump fabricated by compression-coated method: Formulation screen, mechanism research and pharmacokinetic study

In this investigation, time-released monolithic osmotic pump (TMOP) tablets containing diltiazem hydrochloride (DIL) were prepared on the basis of osmotic pumping mechanism. The developed dosage forms were coated by Kollidon®SR-Polyethylene Glycol (PEG) mixtures via compression-coated technology ins...

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Bibliographic Details
Main Authors:	Tiegang Xin, Yang Zhao, Hengpan Jing, Wenji Zhang, Yunyun Gao, Xinggang Yang, Xukai Qu, Weisan Pan
Format:	Article
Language:	English
Published:	Elsevier 2014-08-01
Series:	Asian Journal of Pharmaceutical Sciences
Subjects:	Time-released Osmotic pump Compression-coated Central composite design Pharmacokinetic
Online Access:	http://www.sciencedirect.com/science/article/pii/S1818087614000257

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