TYK2 in Cancer Metastases: Genomic and Proteomic Discovery

TYK2 in Cancer Metastases: Genomic and Proteomic Discovery

Advances in genomic analysis and proteomic tools have rapidly expanded identification of biomarkers and molecular targets important to cancer development and metastasis. On an individual basis, personalized medicine approaches allow better characterization of tumors and patient prognosis, leading to...

Full description

Bibliographic Details
Main Authors:	Dana C. Borcherding, Kevin He, Neha V. Amin, Angela C. Hirbe
Format:	Article
Language:	English
Published:	MDPI AG 2021-08-01
Series:	Cancers
Subjects:	tyrosine kinase-2 TYK2 cancer metastasis genomics proteomics
Online Access:	https://www.mdpi.com/2072-6694/13/16/4171

Similar Items

TYK2 Promoter Variant and Diabetes Mellitus in the Japanese
by: Seiho Nagafuchi, et al.
Published: (2015-07-01)

TYK2 promotes malignant peripheral nerve sheath tumor progression through inhibition of cell death
by: Wenjing Qin, et al.
Published: (2019-09-01)

Subtyping of Type 1 Diabetes as Classified by Anti-GAD Antibody, IgE Levels, and Tyrosine kinase 2 (TYK2) Promoter Variant in the Japanese
by: Keiichiro Mine, et al.
Published: (2017-09-01)

A TYK2 Gene Mutation c.2395G>A Leads to TYK2 Deficiency: A Case Report and Literature Review
by: Peilin Wu, et al.
Published: (2020-05-01)

A Missense Mutation rs781536408 (c.2395G>A) of TYK2 Affects Splicing and Causes Skipping of Exon18 in vivo
by: Suqing Chen, et al.
Published: (2021-06-01)

TYK2 Variants in B-Acute Lymphoblastic Leukaemia
by: Edgar Turrubiartes-Martínez, et al.
Published: (2020-11-01)

The TYK2-P1104A Autoimmune Protective Variant Limits Coordinate Signals Required to Generate Specialized T Cell Subsets
by: Jacquelyn A. Gorman, et al.
Published: (2019-01-01)

Mycobacterium Intracellulare Infection Associated with TYK2 Deficiency: A Case Report and Review of the Literature
by: Guo W, et al.
Published: (2020-12-01)

TYK2 in Tumor Immunosurveillance
by: Anzhelika Karjalainen, et al.
Published: (2020-01-01)

Etudes fonctionnelles de Tyk2 dans la voie de signalisation de l'IFNα: analyse d'un nouvel interacteur et d'une mutation activatrice
by: Gakovic, Milica
Published: (2007)

TYK2: An Upstream Kinase of STATs in Cancer
by: Katharina Wöss, et al.
Published: (2019-11-01)

Cannabinoids Alleviate the LPS-Induced Cytokine Storm via Attenuating NLRP3 Inflammasome Signaling and TYK2-Mediated STAT3 Signaling Pathways In Vitro
by: Kovalchuk, I., et al.
Published: (2022)

From Science to Success? Targeting Tyrosine Kinase 2 in Spondyloarthritis and Related Chronic Inflammatory Diseases
by: Dominika Hromadová, et al.
Published: (2021-07-01)

Molecular and genetic studies of the predisposition to the development of psoriasis among the population of the Russian Federation: a study of polymorphisms of TNFAIP3, TNIP1, TYK2 and REL genes
by: A. A. Kubanov, et al.
Published: (2017-08-01)

Bone Metastases of Gastrointestinal Stromal Tumor: A Review of Published Literature
by: Yang J, et al.
Published: (2020-02-01)

Increased expression of claudin-17 promotes a malignant phenotype in hepatocyte via Tyk2/Stat3 signaling and is associated with poor prognosis in patients with hepatocellular carcinoma
by: Lemeng Sun, et al.
Published: (2018-09-01)

Phlorizin treatment attenuates obesity and related disorders through improving BAT thermogenesis
by: Xin Yuan, et al.
Published: (2016-12-01)

Targeting FER Kinase Inhibits Melanoma Growth and Metastasis
by: Iordanka A. Ivanova, et al.
Published: (2019-03-01)

Cirsiliol targets tyrosine kinase 2 to inhibit esophageal squamous cell carcinoma growth in vitro and in vivo
by: Xuechao Jia, et al.
Published: (2021-03-01)

Physiological and pathophysiological aspects of blood platelet activation through CLEC-2 receptor
by: A. A. Martyanov, et al.
Published: (2018-10-01)

Discovery of a Novel Class of Covalent Dual Inhibitors Targeting the Protein Kinases BMX and BTK
by: Michael Forster, et al.
Published: (2020-12-01)

INTEGRATIVE SYSTEM BIOLOGY STUDIES ON HIGH THROUGHPUT GENOMICS AND PROTEOMICS DATASET
by: Sonachalam, Madhankumar
Published: (2012)

The Clinical Efficacy and Safety of Neratinib in Combination with Capecitabine for the Treatment of Adult Patients with Advanced or Metastatic HER2-Positive Breast Cancer
by: Chilà G, et al.
Published: (2021-06-01)

Invadopodia, a Kingdom of Non-Receptor Tyrosine Kinases
by: Trishna Saha, et al.
Published: (2021-08-01)

Somatic Genomic Testing in Patients With Metastatic or Advanced Cancer: ASCO Provisional Clinical Opinion
by: André, F., et al.
Published: (2022)

National Reference Centre for Genomics and Proteomics — Macprogen
by: Plaseska-Karanfilska Dijana
Published: (2012-12-01)

Joint Genomic and Proteomic Analysis Identifies Meta-Trait Characteristics of Virulent and Non-virulent Staphylococcus aureus Strains
by: Emilia A. Bonar, et al.
Published: (2018-09-01)

Gastrointestinal Metastases From Primary Renal Cell Cancer: A Single Center Review
by: Maelle Rony, et al.
Published: (2021-03-01)

Corrigendum: Gastrointestinal Metastases From Primary Renal Cell Cancer: A Single Center Review
by: Maelle Rony, et al.
Published: (2021-06-01)

Renal cell carcinoma with metastases to the external genitalia. Literature review and case report
by: K. V. Menshikov, et al.
Published: (2021-07-01)

Skin Metastasis of Gastrointestinal Stromal Tumors: A Case Series and Literature Review
by: Liu P, et al.
Published: (2020-08-01)

Breast metastasis from medullary thyroid carcinoma in a male patient: case report and review of the literature
by: Stylianos Mandanas, et al.
Published: (2015-05-01)

Genomic and Proteomic Biomarker Discovery in Neurological Disease
by: Travis Dunckley, et al.
Published: (2008-01-01)

Recent Advances in Discovery of New Tyrosine Kinase Inhibitors Using Computational Methods
by: Vesna Rastija
Published: (2019-08-01)

Tyrosine Kinase Signaling in Cancer Metabolism: PKM2 Paradox in the Warburg Effect
by: Elizabeth K. Wiese, et al.
Published: (2018-07-01)

Metabolic Plasticity Is an Essential Requirement of Acquired Tyrosine Kinase Inhibitor Resistance in Chronic Myeloid Leukemia
by: Miriam G. Contreras Mostazo, et al.
Published: (2020-11-01)

Plasmodium vivax Biology: Insights Provided by Genomics, Transcriptomics and Proteomics
by: Catarina Bourgard, et al.
Published: (2018-02-01)

Development of bioleaching: proteomics and genomics approach in metals extraction process
by: M. Azizur Rahman
Published: (2016-08-01)

Imatinib (STI571) Inhibits the Expression of Angiotensin-Converting Enzyme 2 and Cell Entry of the SARS-CoV-2-Derived Pseudotyped Viral Particles
by: You-Zhe Lin, et al.
Published: (2021-06-01)

SIRT2 Contributes to the Resistance of Melanoma Cells to the Multikinase Inhibitor Dasatinib
by: Iwona Karwaciak, et al.
Published: (2019-05-01)