Clinicopathological and Molecular Characteristics of Pleomorphic Invasive Lobular Carcinoma

Pleomorphic invasive lobular carcinoma (PILC) is a distinct morphological and biologically aggressive variant of invasive lobular carcinoma (ILC). We hypothesized that was due to de novo activation of PI3K/Akt/mTOR pathway in PILC resulting in higher proliferation rate and markers of cell cycle acti...

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Bibliographic Details
Main Authors: Jennifer M. Segar, Ritu Pandey, Kiah J. Farr, Raymond Nagle, Lauren LeBeau, Victor J. Gonzalez, Pavani Chalasani
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:International Journal of Breast Cancer
Online Access:http://dx.doi.org/10.1155/2020/8816824

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