Pre-clinical Pharmacokinetic and Metabolomic Analyses of Isorhapontigenin, a Dietary Resveratrol Derivative

Pre-clinical Pharmacokinetic and Metabolomic Analyses of Isorhapontigenin, a Dietary Resveratrol Derivative

Background: Isorhapontigenin (trans–3,5,4′-trihydroxy–3′–methoxystilbene, ISO), a dietary resveratrol (trans–3,5,4′–trihydroxystilbene) derivative, possesses various health-promoting activities. To further evaluate its medicinal potentials, the pharmacokinetic and metabolomic profiles of ISO were ex...

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Bibliographic Details
Main Authors: Yu Dai, Samuel C. M. Yeo, Peter J. Barnes, Louise E. Donnelly, Lai C. Loo, Hai-Shu Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Pharmacology
Subjects:
isorhapontigenin
resveratrol
pharmacokinetics
metabolomics
oral bioavailability
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.00753/full

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