Multidrug-resistant Tuberculosis Burden among the New Tuberculosis Patients in Zhejiang Province: An Observational Study, 2009–2013
Background: Screening on multidrug-resistant tuberculosis (MDR-TB) has been limited to the serious TB subpopulations excluding the new TB patients. This study aimed to examine MDR-TB burden among the new TB patients. Methods: We conducted a study in Zhejiang Province during 2009–2013 to screen for M...
Main Authors: | , , , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Wolters Kluwer
2017-01-01
|
Series: | Chinese Medical Journal |
Subjects: | |
Online Access: | http://www.cmj.org/article.asp?issn=0366-6999;year=2017;volume=130;issue=17;spage=2021;epage=2026;aulast=Peng |
id |
doaj-92f686b583e94fa29ce6619e725b9bc9 |
---|---|
record_format |
Article |
spelling |
doaj-92f686b583e94fa29ce6619e725b9bc92020-11-25T00:48:18ZengWolters KluwerChinese Medical Journal0366-69992017-01-01130172021202610.4103/0366-6999.213413Multidrug-resistant Tuberculosis Burden among the New Tuberculosis Patients in Zhejiang Province: An Observational Study, 2009–2013Ying PengSong-Hua ChenLe ZhangBin ChenMing-Wu ZhangTie-Niu HeFei WangCheng-Liang ChaiLin ZhouYu ZhangXiao-Meng WangZhongwei JiaBackground: Screening on multidrug-resistant tuberculosis (MDR-TB) has been limited to the serious TB subpopulations excluding the new TB patients. This study aimed to examine MDR-TB burden among the new TB patients. Methods: We conducted a study in Zhejiang Province during 2009–2013 to screen for MDR-TB patients among the low MDR-TB risk patients and five subpopulations of high MDR-TB risk patients. The number, prevalence, and trend of MDR-TB were compared while the logistic regression model was used to examine risk factors related to MDR-TB. Results: A total of 200 and 791 MDR-TB cases were, respectively, identified from the 9830 new TB cases and 2372 high-risk suspects who took MDR-TB screening from 2009 to 2013. The MDR-TB rates went down in both of the new TB patients and five MDR-TB high-risk groups over the study time, but the percentage of MDR-TB patients identified from the new TB patients in all diagnosed MDR-TB cases kept stable from 28.3% in 2011 to 27.0% in 2012 to 26.0% in 2013. Conclusions: The study indicated that MDR-TB burden among new TB patients was high, thus screening for MDR-TB among the new TB patients should be recommended in China as well as in the similar situation worldwide.http://www.cmj.org/article.asp?issn=0366-6999;year=2017;volume=130;issue=17;spage=2021;epage=2026;aulast=PengDrug Resistance; Multidrug-resistant Tuberculosis Screening; Tuberculosis |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Ying Peng Song-Hua Chen Le Zhang Bin Chen Ming-Wu Zhang Tie-Niu He Fei Wang Cheng-Liang Chai Lin Zhou Yu Zhang Xiao-Meng Wang Zhongwei Jia |
spellingShingle |
Ying Peng Song-Hua Chen Le Zhang Bin Chen Ming-Wu Zhang Tie-Niu He Fei Wang Cheng-Liang Chai Lin Zhou Yu Zhang Xiao-Meng Wang Zhongwei Jia Multidrug-resistant Tuberculosis Burden among the New Tuberculosis Patients in Zhejiang Province: An Observational Study, 2009–2013 Chinese Medical Journal Drug Resistance; Multidrug-resistant Tuberculosis Screening; Tuberculosis |
author_facet |
Ying Peng Song-Hua Chen Le Zhang Bin Chen Ming-Wu Zhang Tie-Niu He Fei Wang Cheng-Liang Chai Lin Zhou Yu Zhang Xiao-Meng Wang Zhongwei Jia |
author_sort |
Ying Peng |
title |
Multidrug-resistant Tuberculosis Burden among the New Tuberculosis Patients in Zhejiang Province: An Observational Study, 2009–2013 |
title_short |
Multidrug-resistant Tuberculosis Burden among the New Tuberculosis Patients in Zhejiang Province: An Observational Study, 2009–2013 |
title_full |
Multidrug-resistant Tuberculosis Burden among the New Tuberculosis Patients in Zhejiang Province: An Observational Study, 2009–2013 |
title_fullStr |
Multidrug-resistant Tuberculosis Burden among the New Tuberculosis Patients in Zhejiang Province: An Observational Study, 2009–2013 |
title_full_unstemmed |
Multidrug-resistant Tuberculosis Burden among the New Tuberculosis Patients in Zhejiang Province: An Observational Study, 2009–2013 |
title_sort |
multidrug-resistant tuberculosis burden among the new tuberculosis patients in zhejiang province: an observational study, 2009–2013 |
publisher |
Wolters Kluwer |
series |
Chinese Medical Journal |
issn |
0366-6999 |
publishDate |
2017-01-01 |
description |
Background: Screening on multidrug-resistant tuberculosis (MDR-TB) has been limited to the serious TB subpopulations excluding the new TB patients. This study aimed to examine MDR-TB burden among the new TB patients.
Methods: We conducted a study in Zhejiang Province during 2009–2013 to screen for MDR-TB patients among the low MDR-TB risk patients and five subpopulations of high MDR-TB risk patients. The number, prevalence, and trend of MDR-TB were compared while the logistic regression model was used to examine risk factors related to MDR-TB.
Results: A total of 200 and 791 MDR-TB cases were, respectively, identified from the 9830 new TB cases and 2372 high-risk suspects who took MDR-TB screening from 2009 to 2013. The MDR-TB rates went down in both of the new TB patients and five MDR-TB high-risk groups over the study time, but the percentage of MDR-TB patients identified from the new TB patients in all diagnosed MDR-TB cases kept stable from 28.3% in 2011 to 27.0% in 2012 to 26.0% in 2013.
Conclusions: The study indicated that MDR-TB burden among new TB patients was high, thus screening for MDR-TB among the new TB patients should be recommended in China as well as in the similar situation worldwide. |
topic |
Drug Resistance; Multidrug-resistant Tuberculosis Screening; Tuberculosis |
url |
http://www.cmj.org/article.asp?issn=0366-6999;year=2017;volume=130;issue=17;spage=2021;epage=2026;aulast=Peng |
work_keys_str_mv |
AT yingpeng multidrugresistanttuberculosisburdenamongthenewtuberculosispatientsinzhejiangprovinceanobservationalstudy20092013 AT songhuachen multidrugresistanttuberculosisburdenamongthenewtuberculosispatientsinzhejiangprovinceanobservationalstudy20092013 AT lezhang multidrugresistanttuberculosisburdenamongthenewtuberculosispatientsinzhejiangprovinceanobservationalstudy20092013 AT binchen multidrugresistanttuberculosisburdenamongthenewtuberculosispatientsinzhejiangprovinceanobservationalstudy20092013 AT mingwuzhang multidrugresistanttuberculosisburdenamongthenewtuberculosispatientsinzhejiangprovinceanobservationalstudy20092013 AT tieniuhe multidrugresistanttuberculosisburdenamongthenewtuberculosispatientsinzhejiangprovinceanobservationalstudy20092013 AT feiwang multidrugresistanttuberculosisburdenamongthenewtuberculosispatientsinzhejiangprovinceanobservationalstudy20092013 AT chengliangchai multidrugresistanttuberculosisburdenamongthenewtuberculosispatientsinzhejiangprovinceanobservationalstudy20092013 AT linzhou multidrugresistanttuberculosisburdenamongthenewtuberculosispatientsinzhejiangprovinceanobservationalstudy20092013 AT yuzhang multidrugresistanttuberculosisburdenamongthenewtuberculosispatientsinzhejiangprovinceanobservationalstudy20092013 AT xiaomengwang multidrugresistanttuberculosisburdenamongthenewtuberculosispatientsinzhejiangprovinceanobservationalstudy20092013 AT zhongweijia multidrugresistanttuberculosisburdenamongthenewtuberculosispatientsinzhejiangprovinceanobservationalstudy20092013 |
_version_ |
1725256761491849216 |