Prediction of structure of human WNT-CRD (FZD) complex for computational drug repurposing.
The observed genetic alterations of various extracellular and intracellular WNT (Wingless, Int-1 proto-oncogene) signaling components can result in an increase or decrease in gene expression, and hence can be obstructed proficiently. These genetics target sites may include the prevention of WNT-FZD...
Main Authors: | Qurrat U Ain, Umair Seemab, Sajid Rashid, Muhammad Sulaman Nawaz, Mohammad A Kamal |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3556074?pdf=render |
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