Seasonal differences in brown adipose tissue density and pulse rate variability in a thermoneutral environment
Abstract Background Brown adipose tissue (BAT) is sympathetically activated and induces thermogenesis during cold exposure, thereby influencing energy expenditure and body fat levels. The very low frequency (VLF) components of pulse rate variability could be a form of thermogenic sympathetic nervous...
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doaj-9320371a802145aa93b82f3b5b5388012020-11-24T21:18:25ZengBMCJournal of Physiological Anthropology1880-68052018-02-013711710.1186/s40101-018-0166-xSeasonal differences in brown adipose tissue density and pulse rate variability in a thermoneutral environmentShinsuke Nirengi0Naoki Sakane1Shiho Amagasa2Sawako Wakui3Toshiyuki Homma4Yuko Kurosawa5Takafumi Hamaoka6Division of Preventive Medicine, Clinical Research Institute, National Hospital Organization Kyoto Medical CenterDivision of Preventive Medicine, Clinical Research Institute, National Hospital Organization Kyoto Medical CenterDepartment of Preventive Medicine and Public Health, Tokyo Medical UniversityFaculty of Health and Sports Science, Juntendo UniversityFaculty of Sports and Health Science, Daito Bunka UniversityDepartment of Sports Medicine for Health Promotion, Tokyo Medical UniversityDepartment of Sports Medicine for Health Promotion, Tokyo Medical UniversityAbstract Background Brown adipose tissue (BAT) is sympathetically activated and induces thermogenesis during cold exposure, thereby influencing energy expenditure and body fat levels. The very low frequency (VLF) components of pulse rate variability could be a form of thermogenic sympathetic nervous activity, but no clear relationship has yet been reported between VLF activity and BAT density. We therefore aimed to evaluate the association between them. Methods We enrolled 20 adults in winter and 20 matched adults in summer. We assessed BAT densities based on total hemoglobin concentrations ([total-Hb]) measured with near-infrared time-resolved spectroscopy. We calculated VLF activity from pulse rate variability measurements. Results BAT density ([total-Hb]; winter 70.5 ± 17.0 μM, summer 57.8 ± 18.3 μM) and VLF activity (winter 6.7 ± 0.8, summer 6.1 ± 0.9) were significantly higher in winter than in summer (P < 0.05). However, there was no significant correlation between VLF activity and BAT density in either season. Conclusion Each parameter exhibited seasonal variation, but we failed to observe any significant correlations.http://link.springer.com/article/10.1186/s40101-018-0166-xNear-infrared time-resolved spectroscopyBrown adipose tissueSeasonalityAutonomic nervous system |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Shinsuke Nirengi Naoki Sakane Shiho Amagasa Sawako Wakui Toshiyuki Homma Yuko Kurosawa Takafumi Hamaoka |
spellingShingle |
Shinsuke Nirengi Naoki Sakane Shiho Amagasa Sawako Wakui Toshiyuki Homma Yuko Kurosawa Takafumi Hamaoka Seasonal differences in brown adipose tissue density and pulse rate variability in a thermoneutral environment Journal of Physiological Anthropology Near-infrared time-resolved spectroscopy Brown adipose tissue Seasonality Autonomic nervous system |
author_facet |
Shinsuke Nirengi Naoki Sakane Shiho Amagasa Sawako Wakui Toshiyuki Homma Yuko Kurosawa Takafumi Hamaoka |
author_sort |
Shinsuke Nirengi |
title |
Seasonal differences in brown adipose tissue density and pulse rate variability in a thermoneutral environment |
title_short |
Seasonal differences in brown adipose tissue density and pulse rate variability in a thermoneutral environment |
title_full |
Seasonal differences in brown adipose tissue density and pulse rate variability in a thermoneutral environment |
title_fullStr |
Seasonal differences in brown adipose tissue density and pulse rate variability in a thermoneutral environment |
title_full_unstemmed |
Seasonal differences in brown adipose tissue density and pulse rate variability in a thermoneutral environment |
title_sort |
seasonal differences in brown adipose tissue density and pulse rate variability in a thermoneutral environment |
publisher |
BMC |
series |
Journal of Physiological Anthropology |
issn |
1880-6805 |
publishDate |
2018-02-01 |
description |
Abstract Background Brown adipose tissue (BAT) is sympathetically activated and induces thermogenesis during cold exposure, thereby influencing energy expenditure and body fat levels. The very low frequency (VLF) components of pulse rate variability could be a form of thermogenic sympathetic nervous activity, but no clear relationship has yet been reported between VLF activity and BAT density. We therefore aimed to evaluate the association between them. Methods We enrolled 20 adults in winter and 20 matched adults in summer. We assessed BAT densities based on total hemoglobin concentrations ([total-Hb]) measured with near-infrared time-resolved spectroscopy. We calculated VLF activity from pulse rate variability measurements. Results BAT density ([total-Hb]; winter 70.5 ± 17.0 μM, summer 57.8 ± 18.3 μM) and VLF activity (winter 6.7 ± 0.8, summer 6.1 ± 0.9) were significantly higher in winter than in summer (P < 0.05). However, there was no significant correlation between VLF activity and BAT density in either season. Conclusion Each parameter exhibited seasonal variation, but we failed to observe any significant correlations. |
topic |
Near-infrared time-resolved spectroscopy Brown adipose tissue Seasonality Autonomic nervous system |
url |
http://link.springer.com/article/10.1186/s40101-018-0166-x |
work_keys_str_mv |
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