High yield expression of catalytically active USP18 (UBP43) using a Trigger Factor fusion system
<p>Abstract</p> <p>Background</p> <p>Covalent linkage of the ubiquitin-like protein ISG15 interferes with viral infection and USP18 is the major protease which specifically removes ISG15 from target proteins. Thus, boosting ISG15 modification by protease inhibition of U...
Main Authors: | Basters Anja, Ketscher Lars, Deuerling Elke, Arkona Christoph, Rademann Jörg, Knobeloch Klaus-Peter, Fritz Günter |
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Format: | Article |
Language: | English |
Published: |
BMC
2012-08-01
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Series: | BMC Biotechnology |
Online Access: | http://www.biomedcentral.com/1472-6750/12/56 |
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