In vitro cytogenetic effects of Hypericum heterophyllum in human peripheral blood lymphocytes
Hypericum species have been used in traditional medicine in Turkey for thousands of years. In order to determine the cytogenetic effects of Hypericum heterophyllum, human lymphocytes were incubated with the aqueous extracts. Mitotic index frequencies and replication index values were increased with...
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Bangladesh Pharmacological Society
2012-04-01
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doaj-933671618fb346cd84745fc3391defe92020-11-25T00:13:13ZengBangladesh Pharmacological SocietyBangladesh Journal of Pharmacology1991-00882012-04-017110.3329/bjp.v7i1.10119In vitro cytogenetic effects of Hypericum heterophyllum in human peripheral blood lymphocytesAfide Öcal0Halil Erhan Eroğlu1Bozok University, Science Institute, Department of Biology, YozgatBozok University, Faculty of Science and Art, Department of Biology, Yozgat Hypericum species have been used in traditional medicine in Turkey for thousands of years. In order to determine the cytogenetic effects of Hypericum heterophyllum, human lymphocytes were incubated with the aqueous extracts. Mitotic index frequencies and replication index values were increased with increasing extract concentrations of H. heterophyllum. The results indicate the cytotoxic effects as well as proliferative effects and suggest that the extracts of the compounds exhibit cytotoxic properties as well as mitotic and proliferative properties. https://www.banglajol.info/index.php/BJP/article/view/10119Hypericum heterophyllumCytogeneticMitotic indexReplication index |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Afide Öcal Halil Erhan Eroğlu |
spellingShingle |
Afide Öcal Halil Erhan Eroğlu In vitro cytogenetic effects of Hypericum heterophyllum in human peripheral blood lymphocytes Bangladesh Journal of Pharmacology Hypericum heterophyllum Cytogenetic Mitotic index Replication index |
author_facet |
Afide Öcal Halil Erhan Eroğlu |
author_sort |
Afide Öcal |
title |
In vitro cytogenetic effects of Hypericum heterophyllum in human peripheral blood lymphocytes |
title_short |
In vitro cytogenetic effects of Hypericum heterophyllum in human peripheral blood lymphocytes |
title_full |
In vitro cytogenetic effects of Hypericum heterophyllum in human peripheral blood lymphocytes |
title_fullStr |
In vitro cytogenetic effects of Hypericum heterophyllum in human peripheral blood lymphocytes |
title_full_unstemmed |
In vitro cytogenetic effects of Hypericum heterophyllum in human peripheral blood lymphocytes |
title_sort |
in vitro cytogenetic effects of hypericum heterophyllum in human peripheral blood lymphocytes |
publisher |
Bangladesh Pharmacological Society |
series |
Bangladesh Journal of Pharmacology |
issn |
1991-0088 |
publishDate |
2012-04-01 |
description |
Hypericum species have been used in traditional medicine in Turkey for thousands of years. In order to determine the cytogenetic effects of Hypericum heterophyllum, human lymphocytes were incubated with the aqueous extracts. Mitotic index frequencies and replication index values were increased with increasing extract concentrations of H. heterophyllum. The results indicate the cytotoxic effects as well as proliferative effects and suggest that the extracts of the compounds exhibit cytotoxic properties as well as mitotic and proliferative properties.
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topic |
Hypericum heterophyllum Cytogenetic Mitotic index Replication index |
url |
https://www.banglajol.info/index.php/BJP/article/view/10119 |
work_keys_str_mv |
AT afideocal invitrocytogeneticeffectsofhypericumheterophylluminhumanperipheralbloodlymphocytes AT halilerhaneroglu invitrocytogeneticeffectsofhypericumheterophylluminhumanperipheralbloodlymphocytes |
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1725395686089818112 |