IN STENT RESTENOSIS (ISR) IN PATIENTS UNDERGOING PERCUTANEOUS CORONARY INTERVENTION (PCI) FOR CORONARY ARTERY DISEASE (CAD)
Objective: To study the frequency of In-Stent Restenosis and its treatment in patients undergoing Percutaneous Coronary Intervention for coronary artery disease. Study Design: Descriptive cross sectional study. Place and Duration of Study: Department of Cardiology, Armed Forces Institute of Ca...
Main Authors: | , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
The Army Press
2020-12-01
|
Series: | Pakistan Armed Forces Medical Journal |
Subjects: | |
Online Access: | https://pafmj.org/index.php/PAFMJ/article/view/6045 |
id |
doaj-933dc641491e4d1db1a71a18e736ce5c |
---|---|
record_format |
Article |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Waseem Raja Naseer Ahmed Samore Mohsin Saif Javeria Kamran Sidra Waheed Naeem Tariq Farhan Tuyyab Abdul Hameed Siddiqui |
spellingShingle |
Waseem Raja Naseer Ahmed Samore Mohsin Saif Javeria Kamran Sidra Waheed Naeem Tariq Farhan Tuyyab Abdul Hameed Siddiqui IN STENT RESTENOSIS (ISR) IN PATIENTS UNDERGOING PERCUTANEOUS CORONARY INTERVENTION (PCI) FOR CORONARY ARTERY DISEASE (CAD) Pakistan Armed Forces Medical Journal coronary artery disease percutaneous coronary intervention restenosis |
author_facet |
Waseem Raja Naseer Ahmed Samore Mohsin Saif Javeria Kamran Sidra Waheed Naeem Tariq Farhan Tuyyab Abdul Hameed Siddiqui |
author_sort |
Waseem Raja |
title |
IN STENT RESTENOSIS (ISR) IN PATIENTS UNDERGOING PERCUTANEOUS CORONARY INTERVENTION (PCI) FOR CORONARY ARTERY DISEASE (CAD) |
title_short |
IN STENT RESTENOSIS (ISR) IN PATIENTS UNDERGOING PERCUTANEOUS CORONARY INTERVENTION (PCI) FOR CORONARY ARTERY DISEASE (CAD) |
title_full |
IN STENT RESTENOSIS (ISR) IN PATIENTS UNDERGOING PERCUTANEOUS CORONARY INTERVENTION (PCI) FOR CORONARY ARTERY DISEASE (CAD) |
title_fullStr |
IN STENT RESTENOSIS (ISR) IN PATIENTS UNDERGOING PERCUTANEOUS CORONARY INTERVENTION (PCI) FOR CORONARY ARTERY DISEASE (CAD) |
title_full_unstemmed |
IN STENT RESTENOSIS (ISR) IN PATIENTS UNDERGOING PERCUTANEOUS CORONARY INTERVENTION (PCI) FOR CORONARY ARTERY DISEASE (CAD) |
title_sort |
in stent restenosis (isr) in patients undergoing percutaneous coronary intervention (pci) for coronary artery disease (cad) |
publisher |
The Army Press |
series |
Pakistan Armed Forces Medical Journal |
issn |
0030-9648 2411-8842 |
publishDate |
2020-12-01 |
description |
Objective: To study the frequency of In-Stent Restenosis and its treatment in patients undergoing Percutaneous Coronary Intervention for coronary artery disease.
Study Design: Descriptive cross sectional study.
Place and Duration of Study: Department of Cardiology, Armed Forces Institute of Cardiology & National Institute of Heart disease (AFIC/NIHD) Rawalpindi, from Jul 2017 to Jul 2019.
Methodology: All the patients who underwent Percutaneous Coronary Intervention for Coronary Artery Disease at our institute were considered for this study. A consecutive sampling method was used and inclusion/exclusion criteria was applied. Following data was obtained; 1) Demographic information and clinical risk factors like history of hypertension, hyperlipidemia, diabetes mellitus, smoking, coronary artery disease characteristics
(number of diseased arteries, bifurcation lesions, calcification, chronic total occlusions-CTO and tortuosity) 3), Stent factors (under expansion, fracture, longitudinal miss, stent gap). Data recording, storage, assessment and analysis was done by using SPSS software version 21.
Results: Among 1332 cases, 50 had In-Stent Restenosis with overall prevalence of 3.75%. Mean age of the patients with In-Stent Restenosis was 58.76 (± 9.97), with 45 (90%) male and 5 (10%) female. Diabetes Mellitus was the commonest risk factor (22.9%) followed by Hypertension (18%). Sixty four percent of the patients (n=32) had Single Vessel Coronary Artery Disease, 14 (28%) had Double Vessel Coronary Artery Disease and 4 (8%) had Tripple Vessel Coronary Artery Disease. Left Anterior Descending was the commonest coronary artery that developed In-Stent Restenosis, followed by Right Coronary Artery and Left Circumflex respectively. Previously deployed stents which developed In-Stent Restenosis showed longitudinal geographical miss in 16%, stent under expansion in 6% and stent gap in 4%. There was statistically significant association (p-value=0.02) between stent length and frequency of In-Stent Restenosis and it was commonest in stents longer than 30 mm. Eighty six percent
(n=43) of In-Stent Restenosis cases in our study group was treated with Drug Eluting Stent followed by Drug Eluting Balloon in 32% and Plain Old Balloon Angioplasty in 22%.
Conclusion: History of diabetes mellitus and greater stent length were major risk factors in developing In-Stent Restenosis in our study. DES was the commonest treatment modality used. |
topic |
coronary artery disease percutaneous coronary intervention restenosis |
url |
https://pafmj.org/index.php/PAFMJ/article/view/6045 |
work_keys_str_mv |
AT waseemraja instentrestenosisisrinpatientsundergoingpercutaneouscoronaryinterventionpciforcoronaryarterydiseasecad AT naseerahmedsamore instentrestenosisisrinpatientsundergoingpercutaneouscoronaryinterventionpciforcoronaryarterydiseasecad AT mohsinsaif instentrestenosisisrinpatientsundergoingpercutaneouscoronaryinterventionpciforcoronaryarterydiseasecad AT javeriakamran instentrestenosisisrinpatientsundergoingpercutaneouscoronaryinterventionpciforcoronaryarterydiseasecad AT sidrawaheed instentrestenosisisrinpatientsundergoingpercutaneouscoronaryinterventionpciforcoronaryarterydiseasecad AT naeemtariq instentrestenosisisrinpatientsundergoingpercutaneouscoronaryinterventionpciforcoronaryarterydiseasecad AT farhantuyyab instentrestenosisisrinpatientsundergoingpercutaneouscoronaryinterventionpciforcoronaryarterydiseasecad AT abdulhameedsiddiqui instentrestenosisisrinpatientsundergoingpercutaneouscoronaryinterventionpciforcoronaryarterydiseasecad |
_version_ |
1717761407142854656 |
spelling |
doaj-933dc641491e4d1db1a71a18e736ce5c2021-09-09T04:31:11ZengThe Army PressPakistan Armed Forces Medical Journal0030-96482411-88422020-12-01704865870doi.org/10.51253/pafmj.v70iSuppl-4.60456045IN STENT RESTENOSIS (ISR) IN PATIENTS UNDERGOING PERCUTANEOUS CORONARY INTERVENTION (PCI) FOR CORONARY ARTERY DISEASE (CAD)Waseem Raja0Naseer Ahmed Samore1Mohsin Saif2Javeria Kamran3Sidra Waheed4Naeem Tariq5Farhan Tuyyab6Abdul Hameed Siddiqui7Armed Forces Institute of Cardiology/National Institute of Heart Disease (AFIC/NIHD)/National University of Medical Sciences (NUMS) Rawalpindi PakistanArmed Forces Institute of Cardiology/National Institute of Heart Disease (AFIC/NIHD)/National University of Medical Sciences (NUMS) Rawalpindi PakistanArmed Forces Institute of Cardiology/National Institute of Heart Disease (AFIC/NIHD)/National University of Medical Sciences (NUMS) Rawalpindi PakistanArmed Forces Institute of Cardiology/National Institute of Heart Disease (AFIC/NIHD)/National University of Medical Sciences (NUMS) Rawalpindi PakistanArmed Forces Institute of Cardiology/National Institute of Heart Disease (AFIC/NIHD)/National University of Medical Sciences (NUMS) Rawalpindi PakistanArmed Forces Institute of Cardiology/National Institute of Heart Disease (AFIC/NIHD)/National University of Medical Sciences (NUMS) Rawalpindi PakistanArmed Forces Institute of Cardiology/National Institute of Heart Disease (AFIC/NIHD)/National University of Medical Sciences (NUMS) Rawalpindi PakistanArmed Forces Institute of Cardiology/National Institute of Heart Disease (AFIC/NIHD)/National University of Medical Sciences (NUMS) Rawalpindi PakistanObjective: To study the frequency of In-Stent Restenosis and its treatment in patients undergoing Percutaneous Coronary Intervention for coronary artery disease. Study Design: Descriptive cross sectional study. Place and Duration of Study: Department of Cardiology, Armed Forces Institute of Cardiology & National Institute of Heart disease (AFIC/NIHD) Rawalpindi, from Jul 2017 to Jul 2019. Methodology: All the patients who underwent Percutaneous Coronary Intervention for Coronary Artery Disease at our institute were considered for this study. A consecutive sampling method was used and inclusion/exclusion criteria was applied. Following data was obtained; 1) Demographic information and clinical risk factors like history of hypertension, hyperlipidemia, diabetes mellitus, smoking, coronary artery disease characteristics (number of diseased arteries, bifurcation lesions, calcification, chronic total occlusions-CTO and tortuosity) 3), Stent factors (under expansion, fracture, longitudinal miss, stent gap). Data recording, storage, assessment and analysis was done by using SPSS software version 21. Results: Among 1332 cases, 50 had In-Stent Restenosis with overall prevalence of 3.75%. Mean age of the patients with In-Stent Restenosis was 58.76 (± 9.97), with 45 (90%) male and 5 (10%) female. Diabetes Mellitus was the commonest risk factor (22.9%) followed by Hypertension (18%). Sixty four percent of the patients (n=32) had Single Vessel Coronary Artery Disease, 14 (28%) had Double Vessel Coronary Artery Disease and 4 (8%) had Tripple Vessel Coronary Artery Disease. Left Anterior Descending was the commonest coronary artery that developed In-Stent Restenosis, followed by Right Coronary Artery and Left Circumflex respectively. Previously deployed stents which developed In-Stent Restenosis showed longitudinal geographical miss in 16%, stent under expansion in 6% and stent gap in 4%. There was statistically significant association (p-value=0.02) between stent length and frequency of In-Stent Restenosis and it was commonest in stents longer than 30 mm. Eighty six percent (n=43) of In-Stent Restenosis cases in our study group was treated with Drug Eluting Stent followed by Drug Eluting Balloon in 32% and Plain Old Balloon Angioplasty in 22%. Conclusion: History of diabetes mellitus and greater stent length were major risk factors in developing In-Stent Restenosis in our study. DES was the commonest treatment modality used.https://pafmj.org/index.php/PAFMJ/article/view/6045coronary artery diseasepercutaneous coronary interventionrestenosis |