HDAC Inhibitors Induce BDNF Expression and Promote Neurite Outgrowth in Human Neural Progenitor Cells-Derived Neurons

HDAC Inhibitors Induce BDNF Expression and Promote Neurite Outgrowth in Human Neural Progenitor Cells-Derived Neurons

Besides its key role in neural development, brain-derived neurotrophic factor (BDNF) is important for long-term potentiation and neurogenesis, which makes it a critical factor in learning and memory. Due to the important role of BDNF in synaptic function and plasticity, an in-house epigenetic librar...

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Bibliographic Details
Main Authors: Amir Bagheri, Parham Habibzadeh, Seyedeh Fatemeh Razavipour, Claude-Henry Volmar, Nancy T. Chee, Shaun P. Brothers, Claes Wahlestedt, Seyed Javad Mowla, Mohammad Ali Faghihi
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:International Journal of Molecular Sciences
Subjects:
HDAC inhibitor
BDNF
neurite outgrowth
human neural progenitor cell
neurodegenerative disorder
epigenetic library
screening
Online Access:http://www.mdpi.com/1422-0067/20/5/1109

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