Clinical Trial of Low Irritative Skin Care Cosmetics in Japanese Subjects with Dry Skin

• Main Authors: Tanaka K, Nagasawa T, Nomura Y, Kubota Y, Miyake A, Kawamura K, Yamaguchi Y
• Format: Article
• Language: English
• Published: Dove Medical Press 2020-11-01
• Series: Clinical, Cosmetic and Investigational Dermatology
• Subjects: skin care; dryness; erythema; humidity retention; quality of life
• Online Access: https://www.dovepress.com/clinical-trial-of-low-irritative-skin-care-cosmetics-in-japanese-subje-peer-reviewed-article-CCID

Kazunori Tanaka,1 Teruaki Nagasawa,1 Yuko Nomura,2 Yoshiki Kubota,1 Akihiko Miyake,1 Kimio Kawamura,1 Yoko Yamaguchi1 1Pharmaceutical Products Research and Development Section, NANOEGG® Research Laboratories, Inc, Kawasaki, Kanagawa, Japan; 2Nomura Dermatology Clinic, Yokohama, Kanagawa, JapanCorrespondence: Yoko YamaguchiPharmaceutical Products Research and Development Section, NANOEGG® Research Laboratories, Inc., Innovation Center of NanoMedicine 4F, 3-25-14 Tono-Machi, Kawasaki-Ku, Kawasaki, Kanagawa 210-0821, JapanTel [phone]Fax [phone]Email [e-mail]: To evaluate whether MediQOL, which was developed as a care cosmetic for sensitive skin, causes a change in skin condition for subjects with dry skin requiring moisture retention.Subjects and Methods: This study includes 20 Japanese subjects with dry skin who required moisture retention, as identified by a dermatologist. The subjects used the novel MediQOL products twice a day for four consecutive weeks. A skin evaluation was performed by a dermatologist, and each subject completed a questionnaire prior to the study period and after two and four weeks of MediQOL use.Results: After four weeks of MediQOL use, alleviation of skin dryness, redness, and itchiness was observed in the subjects. The water/oil content of the skin also improved during the study period.Conclusion: Four weeks of MediQOL use resulted in the alleviation of skin dryness, redness, and itchiness and balanced the water/oil content of the skin. MediQOL is expected to be effective in improving the condition of various skin types, including oily, mixed, and sensitive skin as well as dry skin.Keywords: skin care, dryness, erythema, humidity retention, quality of life