MICROCEPHALY AND MACROCEPHALY. A STUDY ON ANTHROPOMETRIC AND CLINICAL DATA FROM 308 SUBJECTS
Head circumference is the auxological parameter that most correlates with developmental anomalies in childhood. Head circumference (HC) two standard deviations (SD) below or above the mean defines microcephaly and macrocephaly, respectively. The aim of this retrospective study was to explore anthrop...
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Associazione Italiana Giovani Medici
2019-11-01
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doaj-9376d60067e648c8a638452aded9a8d42020-11-25T02:21:20ZengAssociazione Italiana Giovani MediciEuromediterranean Biomedical Journal2279-71652279-71652019-11-01143113413810.3269/1970-5492.2019.14.31MICROCEPHALY AND MACROCEPHALY. A STUDY ON ANTHROPOMETRIC AND CLINICAL DATA FROM 308 SUBJECTS Ettore Piro0University of PalermoHead circumference is the auxological parameter that most correlates with developmental anomalies in childhood. Head circumference (HC) two standard deviations (SD) below or above the mean defines microcephaly and macrocephaly, respectively. The aim of this retrospective study was to explore anthropometric parameters and clinical characteristics among subjects with abnormalities in HC who had been referred for developmental assessment. One hundred and sixty four subjects with microcephaly and 144 subjects with macrocephaly were enrolled from birth to 18 months of age. Head circumference at birth and the association with variables related to maternal health status, gestational age, growth pattern, brain imaging and clinical characteristics were analyzed. In some cases, an etiological diagnosis was made. In the two considered conditions, we found different anthropometric and clinical associations, some of which were statistically significant, with implications for ongoing neurodevelopmental surveillance.http://www.embj.org/embj/microcephaly-and-macrocephaly-a-study-on-anthropometric-and-clinical-data-from-308-subjects/microcephalymacrocephalymegalencephalydevelopmental delaymalformationsyndrome |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Ettore Piro |
spellingShingle |
Ettore Piro MICROCEPHALY AND MACROCEPHALY. A STUDY ON ANTHROPOMETRIC AND CLINICAL DATA FROM 308 SUBJECTS Euromediterranean Biomedical Journal microcephaly macrocephaly megalencephaly developmental delay malformation syndrome |
author_facet |
Ettore Piro |
author_sort |
Ettore Piro |
title |
MICROCEPHALY AND MACROCEPHALY. A STUDY ON ANTHROPOMETRIC AND CLINICAL DATA FROM 308 SUBJECTS |
title_short |
MICROCEPHALY AND MACROCEPHALY. A STUDY ON ANTHROPOMETRIC AND CLINICAL DATA FROM 308 SUBJECTS |
title_full |
MICROCEPHALY AND MACROCEPHALY. A STUDY ON ANTHROPOMETRIC AND CLINICAL DATA FROM 308 SUBJECTS |
title_fullStr |
MICROCEPHALY AND MACROCEPHALY. A STUDY ON ANTHROPOMETRIC AND CLINICAL DATA FROM 308 SUBJECTS |
title_full_unstemmed |
MICROCEPHALY AND MACROCEPHALY. A STUDY ON ANTHROPOMETRIC AND CLINICAL DATA FROM 308 SUBJECTS |
title_sort |
microcephaly and macrocephaly. a study on anthropometric and clinical data from 308 subjects |
publisher |
Associazione Italiana Giovani Medici |
series |
Euromediterranean Biomedical Journal |
issn |
2279-7165 2279-7165 |
publishDate |
2019-11-01 |
description |
Head circumference is the auxological parameter that most correlates with developmental anomalies in childhood. Head circumference (HC) two standard deviations (SD) below or above the mean defines microcephaly and macrocephaly, respectively. The aim of this retrospective study was to explore anthropometric parameters and clinical characteristics among subjects with abnormalities in HC who had been referred for developmental assessment. One hundred and sixty four subjects with microcephaly and 144 subjects with macrocephaly were enrolled from birth to 18 months of age. Head circumference at birth and the association with variables related to maternal health status, gestational age, growth pattern, brain imaging and clinical characteristics were analyzed. In some cases, an etiological diagnosis was made. In the two considered conditions, we found different anthropometric and clinical associations, some of which were statistically significant, with implications for ongoing neurodevelopmental surveillance. |
topic |
microcephaly macrocephaly megalencephaly developmental delay malformation syndrome |
url |
http://www.embj.org/embj/microcephaly-and-macrocephaly-a-study-on-anthropometric-and-clinical-data-from-308-subjects/ |
work_keys_str_mv |
AT ettorepiro microcephalyandmacrocephalyastudyonanthropometricandclinicaldatafrom308subjects |
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1724867046705987584 |