Biocatalytic Synthesis of Chiral Alcohols and Amino Acids for Development of Pharmaceuticals

Biocatalytic Synthesis of Chiral Alcohols and Amino Acids for Development of Pharmaceuticals

Chirality is a key factor in the safety and efficacy of many drug products and thus the production of single enantiomers of drug intermediates and drugs has become increasingly important in the pharmaceutical industry. There has been an increasing awareness of the enormous potential of microorganism...

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Main Author: Ramesh N. Patel
Format: Article
Language:English
Published: MDPI AG 2013-10-01
Series:Biomolecules
Subjects:
biocatalysis
enzymatic processes
chiral intermediates
drugs development
Online Access:http://www.mdpi.com/2218-273X/3/4/741
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spelling doaj-9384e5ea76ae42e6adb5e8fe02b92d512020-11-25T00:21:12ZengMDPI AGBiomolecules2218-273X2013-10-013474177710.3390/biom3040741Biocatalytic Synthesis of Chiral Alcohols and Amino Acids for Development of PharmaceuticalsRamesh N. PatelChirality is a key factor in the safety and efficacy of many drug products and thus the production of single enantiomers of drug intermediates and drugs has become increasingly important in the pharmaceutical industry. There has been an increasing awareness of the enormous potential of microorganisms and enzymes derived there from for the transformation of synthetic chemicals with high chemo-, regio- and enatioselectivities. In this article, biocatalytic processes are described for the synthesis of chiral alcohols and unntural aminoacids for pharmaceuticals.http://www.mdpi.com/2218-273X/3/4/741biocatalysisenzymatic processeschiral intermediatesdrugs development
collection DOAJ
language English
format Article
sources DOAJ
author Ramesh N. Patel
spellingShingle Ramesh N. Patel
Biocatalytic Synthesis of Chiral Alcohols and Amino Acids for Development of Pharmaceuticals
Biomolecules
biocatalysis
enzymatic processes
chiral intermediates
drugs development
author_facet Ramesh N. Patel
author_sort Ramesh N. Patel
title Biocatalytic Synthesis of Chiral Alcohols and Amino Acids for Development of Pharmaceuticals
title_short Biocatalytic Synthesis of Chiral Alcohols and Amino Acids for Development of Pharmaceuticals
title_full Biocatalytic Synthesis of Chiral Alcohols and Amino Acids for Development of Pharmaceuticals
title_fullStr Biocatalytic Synthesis of Chiral Alcohols and Amino Acids for Development of Pharmaceuticals
title_full_unstemmed Biocatalytic Synthesis of Chiral Alcohols and Amino Acids for Development of Pharmaceuticals
title_sort biocatalytic synthesis of chiral alcohols and amino acids for development of pharmaceuticals
publisher MDPI AG
series Biomolecules
issn 2218-273X
publishDate 2013-10-01
description Chirality is a key factor in the safety and efficacy of many drug products and thus the production of single enantiomers of drug intermediates and drugs has become increasingly important in the pharmaceutical industry. There has been an increasing awareness of the enormous potential of microorganisms and enzymes derived there from for the transformation of synthetic chemicals with high chemo-, regio- and enatioselectivities. In this article, biocatalytic processes are described for the synthesis of chiral alcohols and unntural aminoacids for pharmaceuticals.
topic biocatalysis
enzymatic processes
chiral intermediates
drugs development
url http://www.mdpi.com/2218-273X/3/4/741
work_keys_str_mv AT rameshnpatel biocatalyticsynthesisofchiralalcoholsandaminoacidsfordevelopmentofpharmaceuticals
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