The relationship between serum retinol concentrations and subclinical infection in rural Brazilian children

ABSTRACT Objective To evaluate the relationship between serum retinol concentrations and subclinical infection in children from rural settlements. Methods A cross-sectional population-based study was carried out in nine rural settlements in the northeastern region of Brazil, involving 118 children...

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Main Authors: Laísla França da Silva TELES, Adriana de Azevedo PAIVA, Liania Alves LUZIA, Flávia Emília Leite de LIMA-FERREIRA, Cecilia Maria Resende Gonçalves de CARVALHO, Patrícia Helen de Carvalho RONDÓ
Format: Article
Language:English
Published: Pontifícia Universidade Católica de Campinas
Series:Revista de Nutrição
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-52732018000300299&lng=en&tlng=en
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spelling doaj-9398d6667d1a4593b036671688e918572020-11-25T00:33:44ZengPontifícia Universidade Católica de CampinasRevista de Nutrição1678-986531329931010.1590/1678-98652018000300004S1415-52732018000300299The relationship between serum retinol concentrations and subclinical infection in rural Brazilian childrenLaísla França da Silva TELESAdriana de Azevedo PAIVALiania Alves LUZIAFlávia Emília Leite de LIMA-FERREIRACecilia Maria Resende Gonçalves de CARVALHOPatrícia Helen de Carvalho RONDÓABSTRACT Objective To evaluate the relationship between serum retinol concentrations and subclinical infection in children from rural settlements. Methods A cross-sectional population-based study was carried out in nine rural settlements in the northeastern region of Brazil, involving 118 children aged 6 to 59 months. The relationship between serum retinol and C-Reactive Protein levels, an important marker of infectious and inflammatory processes, was investigated by multiple linear regression, controlling for demographic, socioeconomic and nutritional variables. Serum retinol and C-Reactive Protein were measured, respectively, by High Performance Liquid Chromatography and immunoturbidimetric assay in automated equipment. Results Vitamin A deficiency (retinol <0.70μmol/L) was identified in 9.3% of the children. C-Reactive Protein was the only predictor of retinol concentrations in the final regression model, causing a 0.728μmol/L reduction in retinol concentrations in the studied children (p=0.008). Conclusion Vitamin A deficiency is a problem of mild/moderate severity and measures to control infectious diseases in this population are fundamental to prevent and/or combat this problem.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-52732018000300299&lng=en&tlng=enPré-escolarLactantesInfecçãoZona ruralVitamina A
collection DOAJ
language English
format Article
sources DOAJ
author Laísla França da Silva TELES
Adriana de Azevedo PAIVA
Liania Alves LUZIA
Flávia Emília Leite de LIMA-FERREIRA
Cecilia Maria Resende Gonçalves de CARVALHO
Patrícia Helen de Carvalho RONDÓ
spellingShingle Laísla França da Silva TELES
Adriana de Azevedo PAIVA
Liania Alves LUZIA
Flávia Emília Leite de LIMA-FERREIRA
Cecilia Maria Resende Gonçalves de CARVALHO
Patrícia Helen de Carvalho RONDÓ
The relationship between serum retinol concentrations and subclinical infection in rural Brazilian children
Revista de Nutrição
Pré-escolar
Lactantes
Infecção
Zona rural
Vitamina A
author_facet Laísla França da Silva TELES
Adriana de Azevedo PAIVA
Liania Alves LUZIA
Flávia Emília Leite de LIMA-FERREIRA
Cecilia Maria Resende Gonçalves de CARVALHO
Patrícia Helen de Carvalho RONDÓ
author_sort Laísla França da Silva TELES
title The relationship between serum retinol concentrations and subclinical infection in rural Brazilian children
title_short The relationship between serum retinol concentrations and subclinical infection in rural Brazilian children
title_full The relationship between serum retinol concentrations and subclinical infection in rural Brazilian children
title_fullStr The relationship between serum retinol concentrations and subclinical infection in rural Brazilian children
title_full_unstemmed The relationship between serum retinol concentrations and subclinical infection in rural Brazilian children
title_sort relationship between serum retinol concentrations and subclinical infection in rural brazilian children
publisher Pontifícia Universidade Católica de Campinas
series Revista de Nutrição
issn 1678-9865
description ABSTRACT Objective To evaluate the relationship between serum retinol concentrations and subclinical infection in children from rural settlements. Methods A cross-sectional population-based study was carried out in nine rural settlements in the northeastern region of Brazil, involving 118 children aged 6 to 59 months. The relationship between serum retinol and C-Reactive Protein levels, an important marker of infectious and inflammatory processes, was investigated by multiple linear regression, controlling for demographic, socioeconomic and nutritional variables. Serum retinol and C-Reactive Protein were measured, respectively, by High Performance Liquid Chromatography and immunoturbidimetric assay in automated equipment. Results Vitamin A deficiency (retinol <0.70μmol/L) was identified in 9.3% of the children. C-Reactive Protein was the only predictor of retinol concentrations in the final regression model, causing a 0.728μmol/L reduction in retinol concentrations in the studied children (p=0.008). Conclusion Vitamin A deficiency is a problem of mild/moderate severity and measures to control infectious diseases in this population are fundamental to prevent and/or combat this problem.
topic Pré-escolar
Lactantes
Infecção
Zona rural
Vitamina A
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-52732018000300299&lng=en&tlng=en
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