The relationship between serum retinol concentrations and subclinical infection in rural Brazilian children
ABSTRACT Objective To evaluate the relationship between serum retinol concentrations and subclinical infection in children from rural settlements. Methods A cross-sectional population-based study was carried out in nine rural settlements in the northeastern region of Brazil, involving 118 children...
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Pontifícia Universidade Católica de Campinas
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doaj-9398d6667d1a4593b036671688e918572020-11-25T00:33:44ZengPontifícia Universidade Católica de CampinasRevista de Nutrição1678-986531329931010.1590/1678-98652018000300004S1415-52732018000300299The relationship between serum retinol concentrations and subclinical infection in rural Brazilian childrenLaísla França da Silva TELESAdriana de Azevedo PAIVALiania Alves LUZIAFlávia Emília Leite de LIMA-FERREIRACecilia Maria Resende Gonçalves de CARVALHOPatrícia Helen de Carvalho RONDÓABSTRACT Objective To evaluate the relationship between serum retinol concentrations and subclinical infection in children from rural settlements. Methods A cross-sectional population-based study was carried out in nine rural settlements in the northeastern region of Brazil, involving 118 children aged 6 to 59 months. The relationship between serum retinol and C-Reactive Protein levels, an important marker of infectious and inflammatory processes, was investigated by multiple linear regression, controlling for demographic, socioeconomic and nutritional variables. Serum retinol and C-Reactive Protein were measured, respectively, by High Performance Liquid Chromatography and immunoturbidimetric assay in automated equipment. Results Vitamin A deficiency (retinol <0.70μmol/L) was identified in 9.3% of the children. C-Reactive Protein was the only predictor of retinol concentrations in the final regression model, causing a 0.728μmol/L reduction in retinol concentrations in the studied children (p=0.008). Conclusion Vitamin A deficiency is a problem of mild/moderate severity and measures to control infectious diseases in this population are fundamental to prevent and/or combat this problem.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-52732018000300299&lng=en&tlng=enPré-escolarLactantesInfecçãoZona ruralVitamina A |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Laísla França da Silva TELES Adriana de Azevedo PAIVA Liania Alves LUZIA Flávia Emília Leite de LIMA-FERREIRA Cecilia Maria Resende Gonçalves de CARVALHO Patrícia Helen de Carvalho RONDÓ |
spellingShingle |
Laísla França da Silva TELES Adriana de Azevedo PAIVA Liania Alves LUZIA Flávia Emília Leite de LIMA-FERREIRA Cecilia Maria Resende Gonçalves de CARVALHO Patrícia Helen de Carvalho RONDÓ The relationship between serum retinol concentrations and subclinical infection in rural Brazilian children Revista de Nutrição Pré-escolar Lactantes Infecção Zona rural Vitamina A |
author_facet |
Laísla França da Silva TELES Adriana de Azevedo PAIVA Liania Alves LUZIA Flávia Emília Leite de LIMA-FERREIRA Cecilia Maria Resende Gonçalves de CARVALHO Patrícia Helen de Carvalho RONDÓ |
author_sort |
Laísla França da Silva TELES |
title |
The relationship between serum retinol concentrations and subclinical infection in rural Brazilian children |
title_short |
The relationship between serum retinol concentrations and subclinical infection in rural Brazilian children |
title_full |
The relationship between serum retinol concentrations and subclinical infection in rural Brazilian children |
title_fullStr |
The relationship between serum retinol concentrations and subclinical infection in rural Brazilian children |
title_full_unstemmed |
The relationship between serum retinol concentrations and subclinical infection in rural Brazilian children |
title_sort |
relationship between serum retinol concentrations and subclinical infection in rural brazilian children |
publisher |
Pontifícia Universidade Católica de Campinas |
series |
Revista de Nutrição |
issn |
1678-9865 |
description |
ABSTRACT Objective To evaluate the relationship between serum retinol concentrations and subclinical infection in children from rural settlements. Methods A cross-sectional population-based study was carried out in nine rural settlements in the northeastern region of Brazil, involving 118 children aged 6 to 59 months. The relationship between serum retinol and C-Reactive Protein levels, an important marker of infectious and inflammatory processes, was investigated by multiple linear regression, controlling for demographic, socioeconomic and nutritional variables. Serum retinol and C-Reactive Protein were measured, respectively, by High Performance Liquid Chromatography and immunoturbidimetric assay in automated equipment. Results Vitamin A deficiency (retinol <0.70μmol/L) was identified in 9.3% of the children. C-Reactive Protein was the only predictor of retinol concentrations in the final regression model, causing a 0.728μmol/L reduction in retinol concentrations in the studied children (p=0.008). Conclusion Vitamin A deficiency is a problem of mild/moderate severity and measures to control infectious diseases in this population are fundamental to prevent and/or combat this problem. |
topic |
Pré-escolar Lactantes Infecção Zona rural Vitamina A |
url |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-52732018000300299&lng=en&tlng=en |
work_keys_str_mv |
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