A Specific PfEMP1 Is Expressed in P. falciparum Sporozoites and Plays a Role in Hepatocyte Infection
Summary: Heterochromatin plays a central role in the process of immune evasion, pathogenesis, and transmission of the malaria parasite Plasmodium falciparum during blood stage infection. Here, we use ChIP sequencing to demonstrate that sporozoites from mosquito salivary glands expand heterochromatin...
Main Authors: | Gigliola Zanghì, Shruthi S. Vembar, Sebastian Baumgarten, Shuai Ding, Julien Guizetti, Jessica M. Bryant, Denise Mattei, Anja T.R. Jensen, Laurent Rénia, Yun Shan Goh, Robert Sauerwein, Cornelus C. Hermsen, Jean-François Franetich, Mallaury Bordessoulles, Olivier Silvie, Valérie Soulard, Olivier Scatton, Patty Chen, Salah Mecheri, Dominique Mazier, Artur Scherf |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2018-03-01
|
Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124718302705 |
Similar Items
-
Interaction of PfEMP1 with the Human Immune System and the Prospect of PfEMP1-based Vaccine for Malaria
by: Magale, Hussein Issak
Published: (2016) -
Antibodies against PfEMP1, RIFIN, MSP3 and GLURP are acquired during controlled Plasmodium falciparum malaria infections in naïve volunteers.
by: Louise Turner, et al.
Published: (2011-01-01) -
Plasmodium falciparum expressing domain cassette 5 type PfEMP1 (DC5-PfEMP1) bind PECAM1.
by: Sanne S Berger, et al.
Published: (2013-01-01) -
The variant antigen, PfEMP1 and the biology of Plasmodium falciparum
by: Tiwari, Bela
Published: (1998) -
Structure of the PfEMP1:EPCR complex and inhibition of the interaction
by: Lau, Clinton Kwun Yau
Published: (2015)