Antibacterial Co(II), Ni(II), Cu(II) and Zn(II) complexes with biacetyl-derived Schiff bases
The condensation reactions of biacetyl with ortho-hydroxyaniline and 2-aminobenzoic acid to form bidendate NO donor Schiff bases were studied. The prepared Schiff base ligands were further utilized for the formation of metal chelates having the general formula [ML2(H2O)2] where M = Co(II), Ni(II), C...
Main Authors: | , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Serbian Chemical Society
2010-08-01
|
Series: | Journal of the Serbian Chemical Society |
Subjects: | |
Online Access: | http://www.shd.org.rs/JSCS/Vol75/No8/06_4600_4032.pdf |
id |
doaj-93da47eed9dd4f6e8c105c7ea0e3e148 |
---|---|
record_format |
Article |
spelling |
doaj-93da47eed9dd4f6e8c105c7ea0e3e1482020-11-24T23:43:15ZengSerbian Chemical Society Journal of the Serbian Chemical Society0352-51392010-08-0175810751084Antibacterial Co(II), Ni(II), Cu(II) and Zn(II) complexes with biacetyl-derived Schiff basesMUHAMMAD IMRANLIVIU MITUSHOOMAILA LATIFZAID MAHMOODIMTIAZ NAIMATSANA S. ZAMANSURRYA FATIMAThe condensation reactions of biacetyl with ortho-hydroxyaniline and 2-aminobenzoic acid to form bidendate NO donor Schiff bases were studied. The prepared Schiff base ligands were further utilized for the formation of metal chelates having the general formula [ML2(H2O)2] where M = Co(II), Ni(II), Cu(II) and Zn(II) and L = HL1 and HL2. These new compounds were characterized by conductance measurements, magnetic susceptibility measurements, elemental analysis, and IR, 1H-NMR, 13C-NMR and electronic spectroscopy. Both Schiff base ligands were found to have a mono-anionic bidentate nature and octahedral geometry was assigned to all metal complexes. All the complexes contained coordinated water which was lost at 141–160 °C. These compounds were also screened for their in vitro antibacterial activity against four bacterial species, namely: Escherichia coli, Staphylococcus aureus, Salmonella typhi and Bacillus subtilis. The metal complexes were found to have greater antibacterial activity than the uncomplexed Schiff base ligands.http://www.shd.org.rs/JSCS/Vol75/No8/06_4600_4032.pdfSchiff basebiacetylmetal ionantibacterial activity |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
MUHAMMAD IMRAN LIVIU MITU SHOOMAILA LATIF ZAID MAHMOOD IMTIAZ NAIMAT SANA S. ZAMAN SURRYA FATIMA |
spellingShingle |
MUHAMMAD IMRAN LIVIU MITU SHOOMAILA LATIF ZAID MAHMOOD IMTIAZ NAIMAT SANA S. ZAMAN SURRYA FATIMA Antibacterial Co(II), Ni(II), Cu(II) and Zn(II) complexes with biacetyl-derived Schiff bases Journal of the Serbian Chemical Society Schiff base biacetyl metal ion antibacterial activity |
author_facet |
MUHAMMAD IMRAN LIVIU MITU SHOOMAILA LATIF ZAID MAHMOOD IMTIAZ NAIMAT SANA S. ZAMAN SURRYA FATIMA |
author_sort |
MUHAMMAD IMRAN |
title |
Antibacterial Co(II), Ni(II), Cu(II) and Zn(II) complexes with biacetyl-derived Schiff bases |
title_short |
Antibacterial Co(II), Ni(II), Cu(II) and Zn(II) complexes with biacetyl-derived Schiff bases |
title_full |
Antibacterial Co(II), Ni(II), Cu(II) and Zn(II) complexes with biacetyl-derived Schiff bases |
title_fullStr |
Antibacterial Co(II), Ni(II), Cu(II) and Zn(II) complexes with biacetyl-derived Schiff bases |
title_full_unstemmed |
Antibacterial Co(II), Ni(II), Cu(II) and Zn(II) complexes with biacetyl-derived Schiff bases |
title_sort |
antibacterial co(ii), ni(ii), cu(ii) and zn(ii) complexes with biacetyl-derived schiff bases |
publisher |
Serbian Chemical Society |
series |
Journal of the Serbian Chemical Society |
issn |
0352-5139 |
publishDate |
2010-08-01 |
description |
The condensation reactions of biacetyl with ortho-hydroxyaniline and 2-aminobenzoic acid to form bidendate NO donor Schiff bases were studied. The prepared Schiff base ligands were further utilized for the formation of metal chelates having the general formula [ML2(H2O)2] where M = Co(II), Ni(II), Cu(II) and Zn(II) and L = HL1 and HL2. These new compounds were characterized by conductance measurements, magnetic susceptibility measurements, elemental analysis, and IR, 1H-NMR, 13C-NMR and electronic spectroscopy. Both Schiff base ligands were found to have a mono-anionic bidentate nature and octahedral geometry was assigned to all metal complexes. All the complexes contained coordinated water which was lost at 141–160 °C. These compounds were also screened for their in vitro antibacterial activity against four bacterial species, namely: Escherichia coli, Staphylococcus aureus, Salmonella typhi and Bacillus subtilis. The metal complexes were found to have greater antibacterial activity than the uncomplexed Schiff base ligands. |
topic |
Schiff base biacetyl metal ion antibacterial activity |
url |
http://www.shd.org.rs/JSCS/Vol75/No8/06_4600_4032.pdf |
work_keys_str_mv |
AT muhammadimran antibacterialcoiiniiicuiiandzniicomplexeswithbiacetylderivedschiffbases AT liviumitu antibacterialcoiiniiicuiiandzniicomplexeswithbiacetylderivedschiffbases AT shoomailalatif antibacterialcoiiniiicuiiandzniicomplexeswithbiacetylderivedschiffbases AT zaidmahmood antibacterialcoiiniiicuiiandzniicomplexeswithbiacetylderivedschiffbases AT imtiaznaimat antibacterialcoiiniiicuiiandzniicomplexeswithbiacetylderivedschiffbases AT sanaszaman antibacterialcoiiniiicuiiandzniicomplexeswithbiacetylderivedschiffbases AT surryafatima antibacterialcoiiniiicuiiandzniicomplexeswithbiacetylderivedschiffbases |
_version_ |
1725502450255790080 |