Egg white peptide-based immunotherapy enhances vitamin A metabolism and induces RORγt+ regulatory T cells

Egg white peptide-based immunotherapy enhances vitamin A metabolism and induces RORγt+ regulatory T cells

This study investigates the mechanism by which food peptides are more effective than intact allergens in providing desensitization against food allergy. BALB/c mice sensitized to egg white (EW) were subjected to oral immunotherapy (OIT) with intact and pepsin-hydrolysed EW (EP). Treatment with EP wa...

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Bibliographic Details
Main Authors: Daniel Lozano-Ojalvo, Mónica Martínez-Blanco, Leticia Pérez-Rodríguez, Elena Molina, Carmen Peláez, Teresa Requena, Rosina López-Fandiño
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Journal of Functional Foods
Subjects:
Food allergy
Egg-peptide immunotherapy
Microbiota
Retinoic acid
RORγt
Regulatory T cells
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464618305802

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