Perspectives of tumor-infiltrating lymphocyte treatment in solid tumors

Perspectives of tumor-infiltrating lymphocyte treatment in solid tumors

Abstract Tumor-infiltrating lymphocyte (TIL) therapy is a type of adoptive cellular therapy by harvesting infiltrated lymphocytes from tumors, culturing and amplifying them in vitro and then infusing back to treat patients. Its diverse TCR clonality, superior tumor-homing ability, and low off-target...

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Bibliographic Details
Main Authors: Shuhang Wang, Jingwei Sun, Kun Chen, Peiwen Ma, Qi Lei, Shujun Xing, Zhongzheng Cao, Shujun Sun, Zicheng Yu, Yarong Liu, Ning Li
Format: Article
Language:English
Published: BMC 2021-06-01
Series:BMC Medicine
Subjects:
Tumor infiltration lymphocyte
Cancer treatment
Immunotherapy
Gene editing
Clinical trials
Online Access:https://doi.org/10.1186/s12916-021-02006-4

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