N-(2-Chloropyrimidin-4-yl)-N,2-dimethyl-2H-indazol-6-amine

N-(2-Chloropyrimidin-4-yl)-N,2-dimethyl-2H-indazol-6-amine

In the title compound, C13H12ClN5, which is a derivative of the antitumor agent pazopanib {systematic name: 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzolsulfonamide}, the indazole and pyrimidine fragments form a dihedral angle of 62.63 (5)&am...

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Main Authors: Hao-Fei Qi, Bing-Ni Liu, Mo Liu, Deng-Ke Liu
Format: Article
Language:English
Published: International Union of Crystallography 2010-11-01
Series:Acta Crystallographica Section E
Online Access:http://scripts.iucr.org/cgi-bin/paper?S1600536810042753
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spelling doaj-9410d7fb52704c92a6c0218a6a29608a2020-11-24T21:26:26ZengInternational Union of CrystallographyActa Crystallographica Section E1600-53682010-11-016611o2955o295510.1107/S1600536810042753N-(2-Chloropyrimidin-4-yl)-N,2-dimethyl-2H-indazol-6-amineHao-Fei QiBing-Ni LiuMo LiuDeng-Ke LiuIn the title compound, C13H12ClN5, which is a derivative of the antitumor agent pazopanib {systematic name: 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzolsulfonamide}, the indazole and pyrimidine fragments form a dihedral angle of 62.63 (5)°. In the crystal, pairs of molecules related by twofold rotational symmetry are linked into dimers through π–π interactions between the indazole ring systems [centroid–centroid distance = 3.720 (2) Å]. Weak intermolecular C—H...N hydrogen bonds further assemble these dimers into columns propagated in [001]. http://scripts.iucr.org/cgi-bin/paper?S1600536810042753
collection DOAJ
language English
format Article
sources DOAJ
author Hao-Fei Qi
Bing-Ni Liu
Mo Liu
Deng-Ke Liu
spellingShingle Hao-Fei Qi
Bing-Ni Liu
Mo Liu
Deng-Ke Liu
N-(2-Chloropyrimidin-4-yl)-N,2-dimethyl-2H-indazol-6-amine
Acta Crystallographica Section E
author_facet Hao-Fei Qi
Bing-Ni Liu
Mo Liu
Deng-Ke Liu
author_sort Hao-Fei Qi
title N-(2-Chloropyrimidin-4-yl)-N,2-dimethyl-2H-indazol-6-amine
title_short N-(2-Chloropyrimidin-4-yl)-N,2-dimethyl-2H-indazol-6-amine
title_full N-(2-Chloropyrimidin-4-yl)-N,2-dimethyl-2H-indazol-6-amine
title_fullStr N-(2-Chloropyrimidin-4-yl)-N,2-dimethyl-2H-indazol-6-amine
title_full_unstemmed N-(2-Chloropyrimidin-4-yl)-N,2-dimethyl-2H-indazol-6-amine
title_sort n-(2-chloropyrimidin-4-yl)-n,2-dimethyl-2h-indazol-6-amine
publisher International Union of Crystallography
series Acta Crystallographica Section E
issn 1600-5368
publishDate 2010-11-01
description In the title compound, C13H12ClN5, which is a derivative of the antitumor agent pazopanib {systematic name: 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzolsulfonamide}, the indazole and pyrimidine fragments form a dihedral angle of 62.63 (5)°. In the crystal, pairs of molecules related by twofold rotational symmetry are linked into dimers through π–π interactions between the indazole ring systems [centroid–centroid distance = 3.720 (2) Å]. Weak intermolecular C—H...N hydrogen bonds further assemble these dimers into columns propagated in [001].
url http://scripts.iucr.org/cgi-bin/paper?S1600536810042753
work_keys_str_mv AT haofeiqi n2chloropyrimidin4yln2dimethyl2hindazol6amine
AT bingniliu n2chloropyrimidin4yln2dimethyl2hindazol6amine
AT moliu n2chloropyrimidin4yln2dimethyl2hindazol6amine
AT dengkeliu n2chloropyrimidin4yln2dimethyl2hindazol6amine
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