Diversity of Two Forms of DNA Methylation in the Brain

Diversity of Two Forms of DNA Methylation in the Brain

DNA methylation 5-methylcytosine (5mC) predicts a compacting chromatin inaccessible to transcription. The discovery of 5-hydroxymethylcytosine (5hmC), which is derived from 5mC, adds a new dimension to the mechanism and role of DNA methylation in epigenetics. Genomic evidence indicates that the 5hmC...

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Bibliographic Details
Main Authors: Yuanyuan eChen, Nur eDamayanti, Joseph eIrudayaraj, Kenneth eDunn, Feng C. Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-03-01
Series:Frontiers in Genetics
Subjects:
5-Methylcytosine
Histone Code
confocal microscopy
epigenetics
Chromatin remodeling
5-Hydroxymethylcytosine
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00046/full

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