In vitro differentiation of human embryonic stem cells into ovarian follicle-like cells

In vitro differentiation of human embryonic stem cells into ovarian follicle-like cells

In vitro production of human oocytes for the treatment of female infertility is a goal in reproductive medicine. Here, the authors establish in vitroconditions to generate human ovarian follicle-like cells from human embryonic stem cells.

Bibliographic Details
Main Authors: Dajung Jung, Jie Xiong, Min Ye, Xunsi Qin, Lin Li, Shunfeng Cheng, Mengyuan Luo, Jia Peng, Ji Dong, Fuchou Tang, Wei Shen, Martin M. Matzuk, Kehkooi Kee
Format: Article
Language:English
Published: Nature Publishing Group 2017-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms15680
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spelling doaj-9423d3c6d4db49438f8ef5d3863d05bb2021-05-11T07:30:25ZengNature Publishing GroupNature Communications2041-17232017-06-018111310.1038/ncomms15680In vitro differentiation of human embryonic stem cells into ovarian follicle-like cellsDajung Jung0Jie Xiong1Min Ye2Xunsi Qin3Lin Li4Shunfeng Cheng5Mengyuan Luo6Jia Peng7Ji Dong8Fuchou Tang9Wei Shen10Martin M. Matzuk11Kehkooi Kee12Department of Basic Medical Sciences, Center for Stem Cell Biology and Regenerative Medicine, School of Medicine, Tsinghua UniversityDepartment of Basic Medical Sciences, Center for Stem Cell Biology and Regenerative Medicine, School of Medicine, Tsinghua UniversityDepartment of Basic Medical Sciences, Center for Stem Cell Biology and Regenerative Medicine, School of Medicine, Tsinghua UniversityKey Laboratory of Animal Reproduction and Germplasm Enhancement in Universities of Shandong, College of Animal Science and Technology, Qingdao Agricultural UniversityDepartment of Basic Medical Sciences, Center for Stem Cell Biology and Regenerative Medicine, School of Medicine, Tsinghua UniversityKey Laboratory of Animal Reproduction and Germplasm Enhancement in Universities of Shandong, College of Animal Science and Technology, Qingdao Agricultural UniversityDepartment of Basic Medical Sciences, Center for Stem Cell Biology and Regenerative Medicine, School of Medicine, Tsinghua UniversityDepartments of Pathology & Immunology, Discovery, Baylor College of MedicineBiodynamic Optical Imaging Center & Department of Obstetrics and Gynecology, College of Life Sciences, Third Hospital, Peking UniversityBiodynamic Optical Imaging Center & Department of Obstetrics and Gynecology, College of Life Sciences, Third Hospital, Peking UniversityKey Laboratory of Animal Reproduction and Germplasm Enhancement in Universities of Shandong, College of Animal Science and Technology, Qingdao Agricultural UniversityDepartments of Pathology & Immunology, Discovery, Baylor College of MedicineDepartment of Basic Medical Sciences, Center for Stem Cell Biology and Regenerative Medicine, School of Medicine, Tsinghua UniversityIn vitro production of human oocytes for the treatment of female infertility is a goal in reproductive medicine. Here, the authors establish in vitroconditions to generate human ovarian follicle-like cells from human embryonic stem cells.https://doi.org/10.1038/ncomms15680
collection DOAJ
language English
format Article
sources DOAJ
author Dajung Jung
Jie Xiong
Min Ye
Xunsi Qin
Lin Li
Shunfeng Cheng
Mengyuan Luo
Jia Peng
Ji Dong
Fuchou Tang
Wei Shen
Martin M. Matzuk
Kehkooi Kee
spellingShingle Dajung Jung
Jie Xiong
Min Ye
Xunsi Qin
Lin Li
Shunfeng Cheng
Mengyuan Luo
Jia Peng
Ji Dong
Fuchou Tang
Wei Shen
Martin M. Matzuk
Kehkooi Kee
In vitro differentiation of human embryonic stem cells into ovarian follicle-like cells
Nature Communications
author_facet Dajung Jung
Jie Xiong
Min Ye
Xunsi Qin
Lin Li
Shunfeng Cheng
Mengyuan Luo
Jia Peng
Ji Dong
Fuchou Tang
Wei Shen
Martin M. Matzuk
Kehkooi Kee
author_sort Dajung Jung
title In vitro differentiation of human embryonic stem cells into ovarian follicle-like cells
title_short In vitro differentiation of human embryonic stem cells into ovarian follicle-like cells
title_full In vitro differentiation of human embryonic stem cells into ovarian follicle-like cells
title_fullStr In vitro differentiation of human embryonic stem cells into ovarian follicle-like cells
title_full_unstemmed In vitro differentiation of human embryonic stem cells into ovarian follicle-like cells
title_sort in vitro differentiation of human embryonic stem cells into ovarian follicle-like cells
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2017-06-01
description In vitro production of human oocytes for the treatment of female infertility is a goal in reproductive medicine. Here, the authors establish in vitroconditions to generate human ovarian follicle-like cells from human embryonic stem cells.
url https://doi.org/10.1038/ncomms15680
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AT jiexiong invitrodifferentiationofhumanembryonicstemcellsintoovarianfolliclelikecells
AT minye invitrodifferentiationofhumanembryonicstemcellsintoovarianfolliclelikecells
AT xunsiqin invitrodifferentiationofhumanembryonicstemcellsintoovarianfolliclelikecells
AT linli invitrodifferentiationofhumanembryonicstemcellsintoovarianfolliclelikecells
AT shunfengcheng invitrodifferentiationofhumanembryonicstemcellsintoovarianfolliclelikecells
AT mengyuanluo invitrodifferentiationofhumanembryonicstemcellsintoovarianfolliclelikecells
AT jiapeng invitrodifferentiationofhumanembryonicstemcellsintoovarianfolliclelikecells
AT jidong invitrodifferentiationofhumanembryonicstemcellsintoovarianfolliclelikecells
AT fuchoutang invitrodifferentiationofhumanembryonicstemcellsintoovarianfolliclelikecells
AT weishen invitrodifferentiationofhumanembryonicstemcellsintoovarianfolliclelikecells
AT martinmmatzuk invitrodifferentiationofhumanembryonicstemcellsintoovarianfolliclelikecells
AT kehkooikee invitrodifferentiationofhumanembryonicstemcellsintoovarianfolliclelikecells
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