High failure rate after Beta-tricalcium phosphate grafting for the treatment of femoral head osteonecrosis: a retrospective analysis
Abstract Background Non-vascularized bone grafting is a promising head-preserving technique for younger patients diagnosed as non-traumatic osteonecrosis of the femoral head (NONFH). Among the various types of bone grafting techniques, “light-bulb” procedure grafting with synthetic bone substitute i...
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doaj-94358345a50d468e99c977325d66d3ae2020-11-25T02:01:58ZengBMCBMC Musculoskeletal Disorders1471-24742020-04-012111910.1186/s12891-020-03291-5High failure rate after Beta-tricalcium phosphate grafting for the treatment of femoral head osteonecrosis: a retrospective analysisPei Liu0Xiao-hong Mu1Hua-chen Yu2Jian-lei Guan3Zhao-hui Liu4Wei-guo Wang5Qi-dong Zhang6Wan-shou Guo7Beijing University of Chinese MedicineDepartment Orthopedics 4, Beijing University of Chinese Medicine, Dongzhimen HospitalGraduate School of Peking Union Medical CollegeBeijing University of Chinese MedicineDepartment of Orthopaedic Surgery, Beijing Key Lab Immune-Mediated Inflammatory Diseases, China-Japan Friendship HospitalDepartment of Orthopaedic Surgery, Beijing Key Lab Immune-Mediated Inflammatory Diseases, China-Japan Friendship HospitalDepartment of Orthopaedic Surgery, Beijing Key Lab Immune-Mediated Inflammatory Diseases, China-Japan Friendship HospitalDepartment of Orthopaedic Surgery, Beijing Key Lab Immune-Mediated Inflammatory Diseases, China-Japan Friendship HospitalAbstract Background Non-vascularized bone grafting is a promising head-preserving technique for younger patients diagnosed as non-traumatic osteonecrosis of the femoral head (NONFH). Among the various types of bone grafting techniques, “light-bulb” procedure grafting with synthetic bone substitute is an attractive option. We aimed to assess the effectiveness of using beta-tricalcium phosphate (β-TCP) for the treatment of pre-collapse and early post-collapse lesions NONFH. Methods From April 2010 to June 2014, 33 patients (47 hips) with NONFH were treated using the afore-mentioned technique. The clinical and radiological outcomes were recorded and compared statistically between pre- and post-operation. Harris hip score (HHS) was used to evaluate the clinical results, and Association Research Circulation Osseous (ARCO) stage was applied to assess the radiological outcomes. Results The 5-years survival rate of using β-TCP grafting was accounting for 25.5%. HHS was decreased from 78.47 to 52.87 points, and a very significant worsening of radiological results were revealed (P < 0.05). Two hips collapsed more than 2 mm were awaiting for THA, and 33 of the 47 hips had converted to THAs in an average time to failure of 24.24 months postoperatively. Meanwhile, only 4 hips survived without collapse, and 8 hips collapsed less than 2 mm. After surgery, the time onset of head collapse was 3.65 months on average, and the first conversion to THA was performed at 5 months postoperative. Conclusions Our results suggest that “light-bulb” procedure grafting with β-TCP sticks presented with a high failure rate in the early postoperative period. It is not proposed for the treatment of pre-collapse and early post-collapse lesions NONFH.http://link.springer.com/article/10.1186/s12891-020-03291-5Osteonecrosis of the femoral headBeta-tricalcium phosphateHead-preserving surgery |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Pei Liu Xiao-hong Mu Hua-chen Yu Jian-lei Guan Zhao-hui Liu Wei-guo Wang Qi-dong Zhang Wan-shou Guo |
spellingShingle |
Pei Liu Xiao-hong Mu Hua-chen Yu Jian-lei Guan Zhao-hui Liu Wei-guo Wang Qi-dong Zhang Wan-shou Guo High failure rate after Beta-tricalcium phosphate grafting for the treatment of femoral head osteonecrosis: a retrospective analysis BMC Musculoskeletal Disorders Osteonecrosis of the femoral head Beta-tricalcium phosphate Head-preserving surgery |
author_facet |
Pei Liu Xiao-hong Mu Hua-chen Yu Jian-lei Guan Zhao-hui Liu Wei-guo Wang Qi-dong Zhang Wan-shou Guo |
author_sort |
Pei Liu |
title |
High failure rate after Beta-tricalcium phosphate grafting for the treatment of femoral head osteonecrosis: a retrospective analysis |
title_short |
High failure rate after Beta-tricalcium phosphate grafting for the treatment of femoral head osteonecrosis: a retrospective analysis |
title_full |
High failure rate after Beta-tricalcium phosphate grafting for the treatment of femoral head osteonecrosis: a retrospective analysis |
title_fullStr |
High failure rate after Beta-tricalcium phosphate grafting for the treatment of femoral head osteonecrosis: a retrospective analysis |
title_full_unstemmed |
High failure rate after Beta-tricalcium phosphate grafting for the treatment of femoral head osteonecrosis: a retrospective analysis |
title_sort |
high failure rate after beta-tricalcium phosphate grafting for the treatment of femoral head osteonecrosis: a retrospective analysis |
publisher |
BMC |
series |
BMC Musculoskeletal Disorders |
issn |
1471-2474 |
publishDate |
2020-04-01 |
description |
Abstract Background Non-vascularized bone grafting is a promising head-preserving technique for younger patients diagnosed as non-traumatic osteonecrosis of the femoral head (NONFH). Among the various types of bone grafting techniques, “light-bulb” procedure grafting with synthetic bone substitute is an attractive option. We aimed to assess the effectiveness of using beta-tricalcium phosphate (β-TCP) for the treatment of pre-collapse and early post-collapse lesions NONFH. Methods From April 2010 to June 2014, 33 patients (47 hips) with NONFH were treated using the afore-mentioned technique. The clinical and radiological outcomes were recorded and compared statistically between pre- and post-operation. Harris hip score (HHS) was used to evaluate the clinical results, and Association Research Circulation Osseous (ARCO) stage was applied to assess the radiological outcomes. Results The 5-years survival rate of using β-TCP grafting was accounting for 25.5%. HHS was decreased from 78.47 to 52.87 points, and a very significant worsening of radiological results were revealed (P < 0.05). Two hips collapsed more than 2 mm were awaiting for THA, and 33 of the 47 hips had converted to THAs in an average time to failure of 24.24 months postoperatively. Meanwhile, only 4 hips survived without collapse, and 8 hips collapsed less than 2 mm. After surgery, the time onset of head collapse was 3.65 months on average, and the first conversion to THA was performed at 5 months postoperative. Conclusions Our results suggest that “light-bulb” procedure grafting with β-TCP sticks presented with a high failure rate in the early postoperative period. It is not proposed for the treatment of pre-collapse and early post-collapse lesions NONFH. |
topic |
Osteonecrosis of the femoral head Beta-tricalcium phosphate Head-preserving surgery |
url |
http://link.springer.com/article/10.1186/s12891-020-03291-5 |
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