The influence of the regional basic diet from northeast Brazil on health and nutritional conditions of mice infected with Schistosoma mansoni

• Main Authors: Eridan M. Coutinho, Lucila P.C.G. de Freitas, Frederico G.C. Abath
• Format: Article
• Language: English
• Published: Sociedade Brasileira de Medicina Tropical (SBMT) 1992-03-01
• Series: Revista da Sociedade Brasileira de Medicina Tropical
• Subjects: Schistosoma mansoni; Camundongos; Má-nutrição
• Online Access: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821992000100003&lng=en&tlng=en

Protein nutritionalstatus indicators were studied in weanling albino Swiss mice infected with S. mansoni andfed the Regional Basic Diet (RBD)from Northeast Brazil, a multideficient diet of low-protein content. Each mouse was infected percutaneously with 80 cercariae. The experiment lasted 63 days. The growth curve, food consumption, protein intake, weight gain, Protein Efficiency Ratio (PER) and Net Protein Ratio (NPR) were the parameters investigated. RBD-fed mice showed a marked weight loss, a lower food and protein intake, a slower body weight gain and lower rates of food protein utilization when compared to casein-fed animals. Differences between infected and non-infected mice were not consistent. The present results suggest that the effects of RBD-induced malnutrition on health and nutritional conditions of the mice are more severe than those of Manson's schistosomiasis, in the initial phase of the disease.