Myc linked to dysregulation of cholesterol transport and storage in nonsmall cell lung cancer
Nonsmall cell lung cancer (NSCLC) is a leading cause of cancer-related deaths. While mutations in Kras and overexpression of Myc are commonly found in patients, the role of altered lipid metabolism in lung cancer and its interplay with oncogenic Myc is poorly understood. Here we use a transgenic mou...
Main Authors: | Zoe Hall, Catherine H. Wilson, Deborah L. Burkhart, Tom Ashmore, Gerard I. Evan, Julian L. Griffin |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-11-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520437277 |
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