Evaluation of Myelin Radiotracers in the Lysolecithin Rat Model of Focal Demyelination: Beware of Pitfalls!

Evaluation of Myelin Radiotracers in the Lysolecithin Rat Model of Focal Demyelination: Beware of Pitfalls!

The observation that amyloid radiotracers developed for Alzheimer’s disease bind to cerebral white matter paved the road to nuclear imaging of myelin in multiple sclerosis. The lysolecithin (lysophosphatidylcholine (LPC)) rat model of demyelination proved useful in evaluating and comparing candidate...

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Bibliographic Details
Main Authors:	Min Zhang, Gaëlle Hugon, Caroline Bouillot, Radu Bolbos, Jean-Baptiste Langlois, Thierry Billard, Frédéric Bonnefoi, Biao Li, Luc Zimmer, Fabien Chauveau
Format:	Article
Language:	English
Published:	Hindawi-Wiley 2019-01-01
Series:	Contrast Media & Molecular Imaging
Online Access:	http://dx.doi.org/10.1155/2019/9294586

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