Abatacept enhances blood regulatory B cells of rheumatoid arthritis patients to a level that associates with disease remittance
Abstract Abatacept, an inhibitor of CD28 mediated T-cell activation, has been shown to be effective in controlling inflammation during rheumatoid arthritis (RA). However, its effects on immune regulatory B and T cells (Bregs and Tregs) has not been fully explored. Thirty-one RA patients treated with...
Main Authors: | Maha Fahad Alenazy, Fatemeh Saheb Sharif-Askari, Mohammed A. Omair, Mohammad S. El-Wetidy, Maha A. Omair, Hussam Mitwalli, Saleh Al-Muhsen, Abeer Al-Masri, Qutayba Hamid, Rabih Halwani |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-03-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-021-83615-0 |
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