The Role of Imaging in Planning Treatment for Central Serous Chorioretinopathy
Central serous chorioretinopathy (CSC) is a controversial disease both in terms of clinical classification and choice of therapeutic strategy. Choroidal layers, retinal pigment epithelium (RPE), photoreceptors, and retina are involved to varying degrees. Beyond well-known symptoms raising the clinic...
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doaj-9486d4df2c9642bdb524214926b3307a2021-01-30T00:04:36ZengMDPI AGPharmaceuticals1424-82472021-01-011410510510.3390/ph14020105The Role of Imaging in Planning Treatment for Central Serous ChorioretinopathyStefano Da Da Da Pozzo0Pierluigi Iacono1Alessandro Arrigo2Maurizio Battaglia Battaglia Battaglia Parodi3TS Retina, 34170 Trieste, ItalyIRCCS—Fondazione Bietti, 00198 Rome, ItalyOphthalmology Department, San Raffaele University Hospital, 20132 Milan, ItalyTS Retina, 34170 Trieste, ItalyCentral serous chorioretinopathy (CSC) is a controversial disease both in terms of clinical classification and choice of therapeutic strategy. Choroidal layers, retinal pigment epithelium (RPE), photoreceptors, and retina are involved to varying degrees. Beyond well-known symptoms raising the clinical suspect of CSC and slit-lamp fundus examination, multimodal imaging plays a key role in assessing the extent of chorioretinal structural involvement. Subretinal fluid (SRF) originating from the choroid leaks through one or multiple RPE defects and spreads into the subretinal space. Spontaneous fluid reabsorption is quite common, but in some eyes, resolution can be obtained only after treatment. Multiple therapeutic strategies are available, and extensive research identified the most effective procedures. Imaging has carved a significant role in guiding the choice of the most appropriate strategy for each single CSC eye. Multiple biomarkers have been identified, and all of them represent a diagnostic and prognostic reference point. This review aims to provide an updated and comprehensive analysis of the current scientific knowledge about the role of imaging in planning the treatment in eyes affected by CSC.https://www.mdpi.com/1424-8247/14/2/105central serous chorioretinopathyfluorescein angiographyindocyanine green angiographyfundus autofluorescenceoptical coherence tomography |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Stefano Da Da Da Pozzo Pierluigi Iacono Alessandro Arrigo Maurizio Battaglia Battaglia Battaglia Parodi |
spellingShingle |
Stefano Da Da Da Pozzo Pierluigi Iacono Alessandro Arrigo Maurizio Battaglia Battaglia Battaglia Parodi The Role of Imaging in Planning Treatment for Central Serous Chorioretinopathy Pharmaceuticals central serous chorioretinopathy fluorescein angiography indocyanine green angiography fundus autofluorescence optical coherence tomography |
author_facet |
Stefano Da Da Da Pozzo Pierluigi Iacono Alessandro Arrigo Maurizio Battaglia Battaglia Battaglia Parodi |
author_sort |
Stefano Da Da Da Pozzo |
title |
The Role of Imaging in Planning Treatment for Central Serous Chorioretinopathy |
title_short |
The Role of Imaging in Planning Treatment for Central Serous Chorioretinopathy |
title_full |
The Role of Imaging in Planning Treatment for Central Serous Chorioretinopathy |
title_fullStr |
The Role of Imaging in Planning Treatment for Central Serous Chorioretinopathy |
title_full_unstemmed |
The Role of Imaging in Planning Treatment for Central Serous Chorioretinopathy |
title_sort |
role of imaging in planning treatment for central serous chorioretinopathy |
publisher |
MDPI AG |
series |
Pharmaceuticals |
issn |
1424-8247 |
publishDate |
2021-01-01 |
description |
Central serous chorioretinopathy (CSC) is a controversial disease both in terms of clinical classification and choice of therapeutic strategy. Choroidal layers, retinal pigment epithelium (RPE), photoreceptors, and retina are involved to varying degrees. Beyond well-known symptoms raising the clinical suspect of CSC and slit-lamp fundus examination, multimodal imaging plays a key role in assessing the extent of chorioretinal structural involvement. Subretinal fluid (SRF) originating from the choroid leaks through one or multiple RPE defects and spreads into the subretinal space. Spontaneous fluid reabsorption is quite common, but in some eyes, resolution can be obtained only after treatment. Multiple therapeutic strategies are available, and extensive research identified the most effective procedures. Imaging has carved a significant role in guiding the choice of the most appropriate strategy for each single CSC eye. Multiple biomarkers have been identified, and all of them represent a diagnostic and prognostic reference point. This review aims to provide an updated and comprehensive analysis of the current scientific knowledge about the role of imaging in planning the treatment in eyes affected by CSC. |
topic |
central serous chorioretinopathy fluorescein angiography indocyanine green angiography fundus autofluorescence optical coherence tomography |
url |
https://www.mdpi.com/1424-8247/14/2/105 |
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